Determination of potency and paraspecific effects of Androctonus crassicauda (Olivier, 1807) antivenom against Mesobuthus gibbosus (Brullé, 1832) venom (Scorpiones: Buthidae)
| العنوان: | Determination of potency and paraspecific effects of Androctonus crassicauda (Olivier, 1807) antivenom against Mesobuthus gibbosus (Brullé, 1832) venom (Scorpiones: Buthidae) |
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| المؤلفون: | Y. Cesaretli, S. Yakistiran, Sirri Kar, S. Adiguzel, Kadri Zafer Karaer, O. Ozkan |
| المصدر: | Journal of Venomous Animals and Toxins including Tropical Diseases v.13 n.2 2007 The Journal of venomous animals and toxins including tropical diseases Universidade Estadual Paulista (UNESP) instacron:UNESP Journal of Venomous Animals and Toxins including Tropical Diseases, Volume: 13, Issue: 2, Pages: 500-508, Published: 2007 Journal of Venomous Animals and Toxins including Tropical Diseases, Vol 13, Iss 2, Pp 500-508 (2007) |
| بيانات النشر: | Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP/UNESP), 2007. |
| سنة النشر: | 2007 |
| مصطلحات موضوعية: | lcsh:Arctic medicine. Tropical medicine, lcsh:RC955-962, Antivenom, Scorpion, Venom, Toxicology, Mesobuthus gibbosus, scorpion, Buthidae, lcsh:RA1190-1270, biology.animal, lcsh:Zoology, Potency, lcsh:QL1-991, Envenomation, lcsh:Toxicology. Poisons, antivenom, biology, Traditional medicine, paraspecific activity, Androctonus crassicauda, biology.organism_classification, Infectious Diseases, Animal Science and Zoology, Parasitology |
| الوصف: | Scorpion envenomation remains a real health problem in many countries. In scorpionism cases, it is often recommended that patients be treated with species-specific antivenom. Androctonus crassicauda venom has been used as antigen for antivenom production in Turkey, where this antivenom, called Turkish antivenom, has also been effective in the treatment of envenomation caused by species other than A. crassicauda. The present study aimed at determining the paraspecific effects and potency of the Turkish antivenom against Mesobuthus gibbosus (Brulle, 1832) venom. To assess the venom toxicity and the antivenom efficacy, we determined the Minimum Lethal Dose (MLD) and the Minimum Effective Dose (MED) instead of LD50 and ED50, respectively. Androctonus crassicauda antivenom was capable of neutralizing M. gibbosus venom (20 MLD). This was the first study indicating that A. crassicauda antivenom can be used for the treatment of Mesobuthus gibbosus stings, especially in Aegean Region, Turkey. |
| وصف الملف: | text/html |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e90be28d74d8f20dee7f6440194955ac http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992007000200008 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....e90be28d74d8f20dee7f6440194955ac |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |