Clinical, epidemiological, and spatial characteristics of Vibrio parahaemolyticus diarrhea and cholera in the urban slums of Kolkata, India
| العنوان: | Clinical, epidemiological, and spatial characteristics of Vibrio parahaemolyticus diarrhea and cholera in the urban slums of Kolkata, India |
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| المؤلفون: | John D. Clemens, Mohammad Ali, Debottam Pal, Young Ae You, Dipika Sur, B L Sarkar, G. Balakrish Nair, Byomkesh Manna, Swapan Kumar Niyogi, Sujit K. Bhattacharya, Suman Kanungo |
| المصدر: | Kanungo, Suman; Sur, Dipika; Ali, Mohammad; You, Young; Pal, Debottam; Manna, Byomkesh; et al.(2012). Clinical, epidemiological, and spatial characteristics of Vibrio parahaemolyticus diarrhea and cholera in the urban slums of Kolkata, India. BMC Public Health, 12(1), 830. doi: http://dx.doi.org/10.1186/1471-2458-12-830. Retrieved from: http://www.escholarship.org/uc/item/4z7919z6 BMC Public Health BMC Public Health, Vol 12, Iss 1, p 830 (2012) |
| بيانات النشر: | eScholarship, University of California, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Adult, Diarrhea, Male, medicine.medical_specialty, Adolescent, India, Vibrio parahaemolyticus, medicine.disease_cause, Vibrio cholerae, Kolkata, Cholera, Risk Factors, Environmental health, Poverty Areas, Epidemiology, Medicine, Cluster Analysis, Humans, Child, First episode, Spatial Analysis, biology, business.industry, Transmission (medicine), lcsh:Public aspects of medicine, Urban Health, Public Health, Environmental and Occupational Health, lcsh:RA1-1270, Middle Aged, biology.organism_classification, medicine.disease, Child, Preschool, Population Surveillance, Immunology, Female, medicine.symptom, business, Cholera vaccine, Research Article |
| الوصف: | Background There is not much information on the differences in clinical, epidemiological and spatial characteristics of diarrhea due to V. cholerae and V. parahaemolyticus from non-coastal areas. We investigated the differences in clinical, epidemiological and spatial characteristics of the two Vibrio species in the urban slums of Kolkata, India. Methods The data of a cluster randomized cholera vaccine trial were used. We restricted the analysis to clusters assigned to placebo. Survival analysis of the time to the first episode was used to analyze risk factors for V. parahaemolyticus diarrhea or cholera. A spatial scan test was used to identify high risk areas for cholera and for V. parahaemolyticus diarrhea. Results In total, 54,519 people from the placebo clusters were assembled. The incidence of cholera (1.30/1000/year) was significantly higher than that of V. parahaemolyticus diarrhea (0.63/1000/year). Cholera incidence was inversely related to age, whereas the risk of V. parahaemolyticus diarrhea was age-independent. The seasonality of diarrhea due to the two Vibrio species was similar. Cholera was distinguished by a higher frequency of severe dehydration, and V. parahaemolyticus diarrhea was by abdominal pain. Hindus and those who live in household not using boiled or treated water were more likely to have V. parahaemolyticus diarrhea. Young age, low socioeconomic status, and living closer to a project healthcare facility were associated with an increased risk for cholera. The high risk area for cholera differed from the high risk area for V. parahaemolyticus diarrhea. Conclusion We report coexistence of the two vibrios in the slums of Kolkata. The two etiologies of diarrhea had a similar seasonality but had distinguishing clinical features. The risk factors and the high risk areas for the two diseases differ from one another suggesting different modes of transmission of these two pathogens. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9cbf564999b7cebd3663bca7b74e4c7 http://www.escholarship.org/uc/item/4z7919z6 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....e9cbf564999b7cebd3663bca7b74e4c7 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |