Cohort profile: The Singapore Breast Cancer Cohort (SGBCC), a multi-center breast cancer cohort for evaluation of phenotypic risk factors and genetic markers
| العنوان: | Cohort profile: The Singapore Breast Cancer Cohort (SGBCC), a multi-center breast cancer cohort for evaluation of phenotypic risk factors and genetic markers |
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| المؤلفون: | Shaik Ahmad Buhari, Kee Seng Chia, Mikael Hartman, Wei Sean Yong, Jingmei Li, Ching Wan Chan, Xueling Sim, Soo Chin Lee, Juliana Jia Chuan Chen, Philip Iau, Veronique Kiak Mien Tan, Jin Yee Lee, Geok Hoon Lim, Evan Woo, Chi Wei Mok, Patrick M. Y. Chan, Zhiyan Yan, Sarah Qinghui Lu, Peh Joo Ho, Wai Peng Lee, Preetha Madhukumar, Yen Shing Yeoh, Rebecca Dent, Jaime Chin Mui Seah, Ern Yu Tan, Rob M. van Dam, Su Ming Tan, Benita Kiat Tee Tan, Hui Miao, Swee Ho Lim, Fuh Yong Wong, Thomas Choudary Putti |
| المصدر: | PLoS ONE PLoS ONE, Vol 16, Iss 4, p e0250102 (2021) |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Skin Neoplasms, Epidemiology, Cancer Treatment, Cohort Studies, Geographical Locations, Risk Factors, Surveys and Questionnaires, Breast Tumors, Medicine and Health Sciences, Breast, Longitudinal Studies, Family history, Skin Tumors, Aged, 80 and over, Ovarian Neoplasms, Singapore, Multidisciplinary, Medical record, Cancer Risk Factors, Middle Aged, Prognosis, Oncology, Cohort, Medicine, Female, Cohort study, Research Article, Adult, Genetic Markers, medicine.medical_specialty, Asia, Science, MEDLINE, Breast Neoplasms, Dermatology, Ethnic Epidemiology, Breast cancer, Diagnostic Medicine, Internal medicine, Breast Cancer, medicine, Cancer Detection and Diagnosis, Humans, Medical history, Genetic Predisposition to Disease, Aged, business.industry, Cancers and Neoplasms, medicine.disease, Medical Risk Factors, People and Places, Ovarian cancer, business |
| الوصف: | This article aims to provide a detailed description of the Singapore Breast Cancer Cohort (SGBCC), an ongoing multi-ethnic cohort established with the overarching goal to identify genetic markers for breast cancer risk, prognosis and treatment response, as well as to understand the ethnic differences in disease risk and outcome in an Asian setting. The cohort comprises of breast cancer patients aged 21 years and above from six public hospitals which diagnose and treat nearly 76% breast cancer cases in Singapore. Self-reported data on sociodemographic and lifestyle, reproductive risk factors, medical history and family history of breast or ovarian cancer is collected using a structured questionnaire. Clinical data on tumour characteristics, and treatment modalities are obtained through medical record. Bio-specimens (blood or saliva) is collected at recruitment. Follow-up on survival information is done through routine linkage with the Registry of Births and Deaths. As of 31 December 2016, 7,768 subjects have been recruited to the study with 76% subjects contributed bio-specimens. The SGBCC provides a valuable platform which offers a unique, large and rich resource for new research ideas on breast cancer related phenotypic risk factors and genetic markers. |
| تدمد: | 1932-6203 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea2308cdbef882fc4ebff59fe7bfe70f https://pubmed.ncbi.nlm.nih.gov/33901219 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....ea2308cdbef882fc4ebff59fe7bfe70f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19326203 |
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