Blinding is compromised for transcranial direct current stimulation at 1 mA for 20 min in young healthy adults
| العنوان: | Blinding is compromised for transcranial direct current stimulation at 1 |
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| المؤلفون: | Matthias Mittner, Andrea Antal, Axel Thielscher, Walter Paulus, Josephine Groot, Zsolt Turi, Nya Mehnwolo Boayue, Gábor Csifcsák, Guy E. Hawkins, Alexander Opitz, Per M. Aslaksen, Birte U. Forstmann |
| المساهمون: | Psychology Other Research (FMG), FMG, Brain and Cognition |
| المصدر: | Turi, Z, Csifcsák, G, Boayue, N M, Aslaksen, P, Antal, A, Paulus, W, Groot, J, Hawkins, G E, Forstmann, B, Opitz, A, Thielscher, A & Mittner, M 2019, ' Blinding is compromised for transcranial direct current stimulation at 1 mA for 20 minutes in young healthy adults ', European Journal of Neuroscience, vol. 50, no. 8, pp. 3261-3268 . https://doi.org/10.1111/ejn.14403 European Journal of Neuroscience, 50(8), 3261-3268. Wiley-Blackwell |
| بيانات النشر: | Wiley, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Blinding, active sham tDCS, medicine.medical_treatment, Pain, Stimulation, Placebo, VDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Nevrologi: 752, 050105 experimental psychology, tDCS, Double blind, Young Adult, bepress|Life Sciences|Neuroscience and Neurobiology, 03 medical and health sciences, 0302 clinical medicine, Physical medicine and rehabilitation, Double-Blind Method, medicine, Humans, 0501 psychology and cognitive sciences, blinding, bepress|Life Sciences|Neuroscience and Neurobiology|Cognitive Neuroscience, 030304 developmental biology, Double-blinding, 0303 health sciences, Transcranial direct-current stimulation, business.industry, General Neuroscience, 05 social sciences, Cognition, Awareness, double‐blinding, Active sham, PsyArXiv|Neuroscience|Cognitive Neuroscience, PsyArXiv|Neuroscience, Brain stimulation, VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Neurology: 752, placebo, Female, Perception, transcranial direct current stimulation, business, 030217 neurology & neurosurgery |
| الوصف: | This is the pre-peer reviewed version of the following article: Turi, Z., Csifcsak, G., Boayue, N.M., Aslaksen, P., Antal, A., Paulus, W., ... Mittner, M. (2019). Blinding is compromised for transcranial direct current stimulation at 1 mA for 20 min in young healthy adults. European Journal of Neuroscience, which has been published in final form at https://doi.org/10.1111/ejn.14403. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. Transcranial direct current stimulation (tDCS) is a non‐invasive brain stimulation method that is frequently used to study cortical excitability changes and their impact on cognitive functions in humans. While most stimulators are capable of operating in double‐blind mode, the amount of discomfort experienced during tDCS may break blinding. Therefore, specifically designed sham stimulation protocols are being used. The “fade‐in, short‐stimulation, fade‐out” (FSF) protocol has been used in hundreds of studies and is commonly believed to be indistinguishable from real stimulation applied at 1 mA for 20 min. We analysed subjective reports of 192 volunteers, who either received real tDCS (n = 96) or FSF tDCS (n = 96). Participants reported more discomfort for real tDCS and correctly guessed the condition above chance‐level. These findings indicate that FSF does not ensure complete blinding and that better active sham protocols are needed. |
| وصف الملف: | application/pdf |
| تدمد: | 1460-9568 0953-816X |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eae47c16c9fe5cc3924ac58e1b00744d https://doi.org/10.1111/ejn.14403 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....eae47c16c9fe5cc3924ac58e1b00744d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14609568 0953816X |
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