Enzymatic incorporation of a new base pair into DNA and RNA extends the genetic alphabet
| العنوان: | Enzymatic incorporation of a new base pair into DNA and RNA extends the genetic alphabet |
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| المؤلفون: | Joseph A. Piccirilli, Steven A. Benner, Tilman Krauch, Simon E. Moroney |
| المصدر: | Nature. 343:33-37 |
| بيانات النشر: | Springer Science and Business Media LLC, 1990. |
| سنة النشر: | 1990 |
| مصطلحات موضوعية: | Stereochemistry, Base pair, Molecular Sequence Data, DNA-Directed DNA Polymerase, Nucleic acid secondary structure, Viral Proteins, chemistry.chemical_compound, Purine Nucleotides, Polymerase, chemistry.chemical_classification, Multidisciplinary, Base Sequence, biology, RNA, Hydrogen Bonding, DNA, DNA-Directed RNA Polymerases, Genetic code, Enzyme, Biochemistry, chemistry, Genetic Code, biology.protein, Nucleic Acid Conformation, Pyrimidine Nucleotides, Artificially Expanded Genetic Information System |
| الوصف: | A new Watson-Crick base pair, with a hydrogen bonding pattern different from that in the A.T and G.C base pairs, is incorporated into duplex DNA and RNA by DNA and RNA polymerases and expands the genetic alphabet from 4 to 6 letters. This expansion could lead to RNAs with greater diversity in functional groups and greater catalytic potential. |
| تدمد: | 1476-4687 0028-0836 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb12c54bcc2a90f165e99eaec360eab8 https://doi.org/10.1038/343033a0 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....eb12c54bcc2a90f165e99eaec360eab8 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14764687 00280836 |
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