Validation of the DIGIROP-birth model in a Chinese cohort
| العنوان: | Validation of the DIGIROP-birth model in a Chinese cohort |
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| المؤلفون: | Chao Li, Sizhe Chen, Shaolin Du, Songfu Feng, Xiaohe Lu, Wenbei Ma, He Chen, Rong Wu |
| المصدر: | BMC Ophthalmology, Vol 21, Iss 1, Pp 1-10 (2021) BMC Ophthalmology |
| بيانات النشر: | BMC, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, China, Gestational Age, Retina, Retinopathy of prematurity, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, 030225 pediatrics, Positive predicative value, medicine, Cutoff, Humans, Generalizability theory, Retrospective Studies, Obstetrics, business.industry, Research, Infant, Newborn, Gestational age, Infant, General Medicine, RE1-994, medicine.disease, Low birth weight, Ophthalmology, Cohort, 030221 ophthalmology & optometry, Gestation, Female, medicine.symptom, business, Prediction, Infant, Premature |
| الوصف: | Background We aimed to validate the predictive performance of the DIGIROP-Birth model for identifying treatment-requiring retinopathy of prematurity (TR-ROP) in Chinese preterm infants to evaluate its generalizability across countries and races. Methods We retrospectively reviewed the medical records of preterm infants who were screened for retinopathy of prematurity (ROP) in a single Chinese hospital between June 2015 and August 2020. The predictive performance of the model for TR-ROP was assessed through the construction of a receiver-operating characteristic (ROC) curve and calculating the areas under the ROC curve (AUC), sensitivity, specificity, and positive and negative predictive values. Results Four hundred and forty-two infants (mean (SD) gestational age = 28.8 (1.3) weeks; mean (SD) birth weight = 1237.0 (236.9) g; 64.7% males) were included in the study. Analyses showed that the DIGIROP-Birth model demonstrated less satisfactory performance than previously reported in identifying infants with TR-ROP, with an area under the receiver-operating characteristic curve of 0.634 (95% confidence interval = 0.564–0.705). With a cutoff value of 0.0084, the DIGIROP-Birth model showed a sensitivity of 48/93 (51.6%), which increased to 89/93 (95.7%) after modification with the addition of postnatal risk factors. In infants with a gestational age Conclusions Although the predictive performance was less satisfactory in China than in developed countries, modification of the DIGIROP-Birth model with postnatal risk factors shows promise in improving its efficacy for TR-ROP. The model may also be effective in infants with a younger gestational age or with an extremely low birth weight. |
| اللغة: | English |
| تدمد: | 1471-2415 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb42b7fc800bf37dc3c6bd76800a693b https://doaj.org/article/55980b70a7814587a5927516f012ef2c |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....eb42b7fc800bf37dc3c6bd76800a693b |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14712415 |
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