Variability of average SUV from several hottest voxels is lower than that of SUVmax and SUVpeak

التفاصيل البيبلوغرافية
العنوان: Variability of average SUV from several hottest voxels is lower than that of SUVmax and SUVpeak
المؤلفون: H. de Clermont, Eric Laffon, Roger Marthan, F. Lamare, Irene A. Burger
المصدر: European Radiology. 24:1964-1970
بيانات النشر: Springer Science and Business Media LLC, 2014.
سنة النشر: 2014
مصطلحات موضوعية: Adult, Male, Treatment response, medicine.medical_specialty, Lung Neoplasms, Tumor burden, Standardized uptake value, computer.software_genre, 18f fdg pet, Fluorodeoxyglucose F18, Voxel, Humans, Medicine, Radiology, Nuclear Medicine and imaging, Prospective Studies, Voxel volume, Aged, Neoplasm Staging, business.industry, General Medicine, Repeatability, Pet imaging, Middle Aged, Tumor Burden, Positron-Emission Tomography, Injections, Intravenous, Female, Radiology, Radiopharmaceuticals, business, Nuclear medicine, computer
الوصف: To assess variability of the average standard uptake value (SUV) computed by varying the number of hottest voxels within an 18F-fluorodeoxyglucose (18F-FDG)-positive lesion. This SUV metric was compared with the maximal SUV (SUVmax: the hottest voxel) and peak SUV (SUVpeak: SUVmax and its 26 neighbouring voxels). Twelve lung cancer patients (20 lesions) were analysed using PET dynamic acquisition involving ten successive 2.5-min frames. In each frame and lesion, average SUV obtained from the N = 5, 10, 15, 20, 25 or 30 hottest voxels (SUVmax–N ), SUVmax and SUVpeak were assessed. The relative standard deviations (SDrs) from ten frames were calculated for each SUV metric and lesion, yielding the mean relative SD from 20 lesions for each SUV metric (SDr N , SDrmax and SDrpeak), and hence relative measurement error and repeatability (MEr–R). For each N, SDr N was significantly lower than SDrmax and SDrpeak. SDr N correlated strongly with N: 6.471 × N -0.103 (r = 0.994; P
تدمد: 1432-1084
0938-7994
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb54368f02338fcca174b7a5ec1c28d9
https://doi.org/10.1007/s00330-014-3222-x
حقوق: CLOSED
رقم الأكسشن: edsair.doi.dedup.....eb54368f02338fcca174b7a5ec1c28d9
قاعدة البيانات: OpenAIRE