Chlorpyrifos Exposure and Respiratory Health among Adolescent Agricultural Workers
| العنوان: | Chlorpyrifos Exposure and Respiratory Health among Adolescent Agricultural Workers |
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| المؤلفون: | Diane S. Rohlman, Catherine L. Callahan, MA Al-Batanony, Gaafar M Abdel-Rasoul, Olfat Hendy, James R. Olson, Ahmed A. Ismail, Matthew R. Bonner |
| المصدر: | International Journal of Environmental Research and Public Health, Vol 11, Iss 12, Pp 13117-13129 (2014) International Journal of Environmental Research and Public Health Volume 11 Issue 12 Pages 13117-13129 |
| بيانات النشر: | MDPI AG, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Male, Spirometry, Insecticides, Adolescent, Pyridones, Health, Toxicology and Mutagenesis, Urinary system, Physiology, lcsh:Medicine, Pilot Projects, 010501 environmental sciences, 01 natural sciences, Article, chlorpyrifos, Toxicology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Occupational Exposure, Wheeze, Humans, Medicine, Respiratory sounds, adolescents, Respiratory Sounds, 0105 earth and related environmental sciences, medicine.diagnostic_test, business.industry, Organophosphate, lcsh:R, Public Health, Environmental and Occupational Health, Agriculture, lung function, Odds ratio, 3. Good health, TCPy, 030228 respiratory system, chemistry, Chlorpyrifos, Egypt, medicine.symptom, business, Biomarkers |
| الوصف: | Chlorpyrifos (CPF) is a commonly used organophosphate insecticide (OP). In adults, exposure to OPs has been inconsistently associated with reduced lung function. OP exposure and lung function has not been assessed in adolescents. The objective of this study was to assess CPF exposure and lung function among Egyptian adolescents. We conducted a 10-month study of male adolescent pesticide applicators (n = 38) and non-applicators of similar age (n = 24). Urinary 3,5,6-trichloro-2-pyridinol (TPCy), a CPF-specific metabolite, was analyzed in specimens collected throughout the study. Spirometry was performed twice after pesticide application: day 146, when TCPy levels were elevated and day 269, when TCPy levels were near baseline. Applicators had higher levels of TCPy (mean cumulative TCPy day 146 = 33,217.6 standard deviation (SD) = 49,179.3) than non-applicators (mean cumulative TCPy day 146 = 3290.8 SD = 3994.9). Compared with non-applicators, applicators had higher odds of reporting wheeze, odds ratio = 3.41 (95% CI: 0.70 17.41). Cumulative urinary TCPy was inversely associated with spirometric measurements at day 146, but not at day 269. Although generally non-significant, results were consistent with an inverse association between exposure to CPF and lung function. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1660-4601 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ece9a27b4c141c6b94b503e63a6bc67b http://www.mdpi.com/1660-4601/11/12/13117 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....ece9a27b4c141c6b94b503e63a6bc67b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16604601 |
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