Comparative study of cutaneous leishmaniasis in human immunodeficiency virus (HIV)-infected patients and non-HIV-infected patients in French Guiana
| العنوان: | Comparative study of cutaneous leishmaniasis in human immunodeficiency virus (HIV)-infected patients and non-HIV-infected patients in French Guiana |
|---|---|
| المؤلفون: | Dominique Sainte-Marie, P. Del Giudice, M. Sobesky, Bernard Carme, Roger Pradinaud, F. Bissuel, Jean-Pierre Dedet, E. Clyti, Pierre Couppié |
| المصدر: | British Journal of Dermatology. 151:1165-1171 |
| بيانات النشر: | Oxford University Press (OUP), 2004. |
| سنة النشر: | 2004 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Leishmania guyanensis, Antiprotozoal Agents, Leishmaniasis, Cutaneous, Dermatology, Immunocompromised Host, Cutaneous leishmaniasis, Acquired immunodeficiency syndrome (AIDS), Recurrence, medicine, Humans, Sida, Pentamidine, Aged, AIDS-Related Opportunistic Infections, biology, business.industry, Leishmaniasis, Middle Aged, medicine.disease, biology.organism_classification, CD4 Lymphocyte Count, Treatment Outcome, Lymphangitis, Case-Control Studies, Immunology, Female, Viral disease, business, medicine.drug |
| الوصف: | Summary Background Few data are available on cutaneous leishmaniasis caused by dermotropic species in human immunodeficiency virus (HIV)-infected patients. Objectives To describe nine cases of cutaneous leishmaniasis in HIV+ patients and to compare their clinical features and their response to treatment with those of HIV– patients with the forms of leishmaniasis commonly found in French Guiana. Methods A case–control study was carried out between July 1994 and December 2000 in French Guiana. We compared the following variables in nine HIV-infected patients with leishmaniasis and 27 matched controls: clinical type of leishmaniasis, number of lesions, presence of lymphangitis and adenopathy, the rate of recovery after treatment, and recurrence or reinfection. Results Eight of the HIV-infected patients had localized cutaneous leishmaniasis and one had mucocutaneous leishmaniasis. All of the controls had localized cutaneous leishmaniasis. Leishmania guyanensis was the only species isolated from HIV-infected subjects. HIV–Leishmania coinfected patients had a higher rate of recurrence or reinfection (P 200 CD4+ T cells mm−3) is characterized by a higher rate of recurrence or reinfection and is more difficult to treat than that in HIV– subjects. |
| تدمد: | 1365-2133 0007-0963 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eecc3520fa4dc3a05d498aad9f09592f https://doi.org/10.1111/j.1365-2133.2004.06226.x |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....eecc3520fa4dc3a05d498aad9f09592f |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13652133 00070963 |
|---|