Formulation of Anti-Acne Gel of Moringa oleifera, L. Ethanolic Extract and Antibacterial Test on Staphylococcus epidermidis
| العنوان: | Formulation of Anti-Acne Gel of Moringa oleifera, L. Ethanolic Extract and Antibacterial Test on Staphylococcus epidermidis |
|---|---|
| المؤلفون: | Cahyarani Intan Ramadhani, Dian Eka Ermawati |
| المصدر: | Majalah Farmaseutik; Vol 16, No 2 (2020); 154-162 Journal of Food and Pharmaceutical Sciences; Vol 7, No 1-3 (2019): J. Food Pharm. Sci (January-December) In Press |
| بيانات النشر: | Faculty of Pharmacy, Universitas Gadjah Mada, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | chemistry.chemical_classification, biology, Flavonoid, Organoleptic, Clindamycin, Pharmaceutical Science, biology.organism_classification, Moringa, chemistry, Staphylococcus epidermidis, Maceration (wine), medicine, Food science, Antibacterial activity, moringa leaves, HPMC 4000, gel, Staphylococcus epidermidis, Bacteria, medicine.drug |
| الوصف: | Moringa oleifera L. leaves contain flavonoid, alkaloid, and phenolic compounds which have antibacterial activity. Staphylococcus epidermidis is one of the bacteria that causes acne. The purpose of this study is to compare bacteriostatic ability of the extracts and gel for S. epidermidis bacteria and to get gel formula that can fulfills the physical properties of a good gel. Moringa leaves were extracted with maceration method using ethanol 70% in three days. HPMC 4000 was used as the polymer. Extract was added with variation concentrations of 5, 10, and 15%. Physical evaluation of gel was organoleptic, homogeneity, pH, viscosity, adhesion, and spread tests for 4 weeks. In vitro bacteriostatic activity test with 1% clindamycin gel as positive control and polymer gel as negative control. The result showed that variations concentrations of ethanolic extract of Moringa leaves affected the physical properties of gel including viscosity, pH, adhesion and spreadability. Bacteriostatic activity test of ethanolic extract of Moringa leaf was classified as strong activity, while 15% Moringa leaf ethanol extract gel was classified as moderate activity with average diameter was 9.14 mm |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1410-590X 2614-0063 2339-0948 2089-7200 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6cfc4b6e0b0b9171cbd1ec7a212075 https://journal.ugm.ac.id/majalahfarmaseutik/article/view/50319 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....ef6cfc4b6e0b0b9171cbd1ec7a212075 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 1410590X 26140063 23390948 20897200 |
|---|