Idiopathic multifocal myocardial atrophy with fibrosis and fatty infiltration involving Purkinje fibres in a 13‐year‐old Arabian broodmare: Histopathological features
| العنوان: | Idiopathic multifocal myocardial atrophy with fibrosis and fatty infiltration involving Purkinje fibres in a 13‐year‐old Arabian broodmare: Histopathological features |
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| المؤلفون: | Mohammad Ali, Wasiq Mehmood, Masa-aki Oikawa, Midori Goto Asakawa |
| المصدر: | Veterinary Medicine and Science |
| بيانات النشر: | Wiley, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Pathology, medicine.medical_specialty, Myocarditis, sudden death, Case Report, Autopsy, Case Reports, Arabian horses, Sudden death, Purkinje Fibers, cardiopathology, Atrophy, Fibrosis, medicine, Animals, Horses, Interventricular septum, Myocardial Degeneration, General Veterinary, business.industry, medicine.disease, Purkinje fibres, medicine.anatomical_structure, cardiac conduction system, histopathology, Female, Horse Diseases, Myocardial fibrosis, Cardiomyopathies, business |
| الوصف: | Myocardial atrophy with fibrosis and fatty infiltration involving the cardiac conduction system is relatively unusual in horses. We herein report of such a case in a 13‐year‐old Arabian broodmare that had spontaneously died on a paddock. An autopsy revealed multifocal myocardial atrophy with concomitant fibrosis and fatty infiltration in both the ventricles and interventricular septum. The Purkinje fibres in the ventricles and interventricular septum were surrounded by thick fibrous or adipose tissues adjacent to atrophic myocardial cells. Myocardial fibrosis and fatty infiltration were likely secondary to myocardial atrophy, occurring as a pathological response triggered by the repair of muscular wall injury. However, there were no major vascular pathologies (e.g. atherosclerosis and arteriosclerosis); hence, the pathogenesis of myocardial atrophy was unclear. There was no evidence of myocardial atrophy - induced pathologies such as infarct, ischaemic lesions, myocardial degeneration, myocarditis and endocarditis. However, such an unusual histopathological pattern may be associated with rapid clinical deterioration and death. Idiopathic multifocal myocardial atrophy. |
| تدمد: | 2053-1095 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f08b95ee12c36e9e540ed53391e0d155 https://doi.org/10.1002/vms3.350 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....f08b95ee12c36e9e540ed53391e0d155 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20531095 |
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