Predictive Factors for the Development or Regression of Fatty Liver in Japanese Adults
| العنوان: | Predictive Factors for the Development or Regression of Fatty Liver in Japanese Adults |
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| المؤلفون: | Masayuki Osabe, Keisuke Sera, Katsuhisa Omagari, Seiko Nagaoka, Miki Sato, Shigeko Kato, Takehiko Kadota, Yukiko Sadakane, Shun-ichi Morikawa, Mizuho Hamasaki, Jun-ichi Masuda |
| المصدر: | Journal of Clinical Biochemistry and Nutrition |
| بيانات النشر: | The Society for Free Radical Research Japan, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | medicine.medical_specialty, Clinical Biochemistry, Medicine (miscellaneous), Physiology, Blood sugar, body mass index, Logistic regression, metabolic syndrome, chemistry.chemical_compound, Internal medicine, Diabetes mellitus, medicine, fatty liver, Nutrition and Dietetics, Triglyceride, business.industry, Fatty liver, non-alcoholic fatty liver disease, medicine.disease, Obesity, Endocrinology, chemistry, Original Article, percentage body fat, Metabolic syndrome, business, Body mass index |
| الوصف: | Fatty liver is commonly associated with alcohol or metabolic syndrome. We aimed to examine the longitudinal aspects of fatty liver, and clarify the independent predictors for the development or regression of fatty liver. In the present study, the clinical features of 1578 Japanese adults (1208 men and 370 women; 35 to 69 years of age) who visited our center both in 2000 and 2007-2008 were recorded and compared, including liver status diagnosed by ultrasonography. Of the 1578 participants, 217 (13.8%) showed fatty liver development, and 74 (4.7%) showed fatty liver regression. Logistic regression analysis revealed that body mass index and percentage body fat were strongly associated with the development or regression of fatty liver. Metabolic syndrome-related disorders such as serum levels of total cholesterol, triglyceride, uric acid, and fasting blood glucose were also associated with clinical course to some degree. However, the history of alcohol intake, the presence of metabolic syndrome, blood pressure, and habitual physical exercise were not independent predictors for the development or regression of fatty liver. Our present data suggest that control of body weight in men and the percentage body fat in women are particularly important for the prevention or treatment of fatty liver. |
| تدمد: | 1880-5086 0912-0009 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f17e70daeba5db672a60c23b2655a008 https://doi.org/10.3164/jcbn.08-269 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....f17e70daeba5db672a60c23b2655a008 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18805086 09120009 |
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