Artificial vision by direct optic nerve electrode (AV-DONE) implantation in a blind patient with retinitis pigmentosa
| العنوان: | Artificial vision by direct optic nerve electrode (AV-DONE) implantation in a blind patient with retinitis pigmentosa |
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| المؤلفون: | Takashi Fujikado, Hugo Quiroz-Mercado, Motoki Ozawa, Motohiro Kamei, Hirokazu Sakaguchi, Eiji Yonezawa, Orlando Ustáriz-González, C. Cecilia-Gonzalez, Yasuo Tano |
| المصدر: | Journal of Artificial Organs. 12:206-209 |
| بيانات النشر: | Springer Science and Business Media LLC, 2009. |
| سنة النشر: | 2009 |
| مصطلحات موضوعية: | Adult, medicine.medical_specialty, Visual perception, genetic structures, Biomedical Engineering, Prosthesis Implantation, Medicine (miscellaneous), Audiology, Blindness, Biomaterials, Ophthalmology, Retinitis pigmentosa, medicine, Humans, business.industry, Optic Nerve, medicine.disease, Electric Stimulation, eye diseases, Electrodes, Implanted, medicine.anatomical_structure, Phosphene, Visual prosthesis, Electrode, Visual Perception, Optic nerve, Feasibility Studies, Female, Cardiology and Cardiovascular Medicine, business, Retinitis Pigmentosa, Optic disc |
| الوصف: | The purpose of this study was to evaluate the efficacy and safety of artificial vision by using a direct optic nerve electrode (AV-DONE) in a blind patient with retinitis pigmentosa (RP). This device, comprising three wire electrodes (0.05 mm in diameter), was implanted into the optic disc of a patient with RP with no light perception vision and the device was left implanted. Six months later, visual sensations were elicited by electrical stimulation through each electrode and the thresholds for the phosphene perception elicited by pulses of 0.25-ms duration/phase and a pulse frequency of 320 Hz were 30, 5, and 70 microA for each electrode. The phosphenes, which ranged in size from that of a match head to an apple, were round, oval, or linear, primarily yellow, and focally distributed. The area of the phosphenes changed when the electrical stimulation was supplied from different electrodes. No complications arose during the follow-up period. Localized visual sensations were produced in a blind patient with advanced RP, suggesting that our system could lead to the development of a useful visual prosthesis system. |
| تدمد: | 1619-0904 1434-7229 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f4f0f780bf7b6e59a806b7995680cc https://doi.org/10.1007/s10047-009-0467-2 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....f1f4f0f780bf7b6e59a806b7995680cc |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 16190904 14347229 |
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