Serum ionic fluoride levels in haemodialysis and continuous ambulatory peritoneal dialysis patients
| العنوان: | Serum ionic fluoride levels in haemodialysis and continuous ambulatory peritoneal dialysis patients |
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| المؤلفون: | Abdul Rauf Chaudhary, Ahmad Hassan Mitwalli, Suleiman Al-Mohaya, S. A. Al-Majed, N. Memon, Hassan Abu-Aisha, Jamal Al-Wakeel, S. Huraib |
| المصدر: | Nephrology Dialysis Transplantation. 12:1420-1424 |
| بيانات النشر: | Oxford University Press (OUP), 1997. |
| سنة النشر: | 1997 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, medicine.medical_treatment, Gastroenterology, Peritoneal dialysis, Fluorides, Peritoneal Dialysis, Continuous Ambulatory, Renal Dialysis, Water Supply, Internal medicine, medicine, Humans, Renal osteodystrophy, Risk factor, Dialysis, Transplantation, business.industry, Continuous ambulatory peritoneal dialysis, Middle Aged, medicine.disease, Surgery, Nephrology, Ambulatory, Kidney Failure, Chronic, Female, Hemodialysis, business, Kidney disease |
| الوصف: | High serum fluoride (F-) in patients with chronic renal failure (CRF) and end-stage renal disease (ESRD) is associated with risk of renal osteodystrophy and other bone changes. This study was done to determine F- in normal healthy controls and patients with ESRD on haemodialysis (HD) or peritoneal dialysis (PD). Seventeen healthy controls (12 males, 5 females) and 39 ESRD patients on dialysis (17 males, 22 females) were recruited in the study in a community with 47.4 +/- 3.28 microM/l (range 44-51 microM/l) of F- content in drinking water. Control subjects showed a mean serum F- concentration of 1.08 +/- 0.350 microM/l. Males in control group showed slightly higher F- levels (1.15 +/- 0.334, range 0.55-1.9 microM/l) than females (0.92 +/- 0.370, range 0.6-1.5 microM/l). Mean serum F- concentration did not correlate significantly with age and sex among control subjects, whereas such correlation was observed in patients with ESRD on dialysis. Mean serum F- concentration was significantly higher in patients on dialysis (2.67 +/- 1.09, range 0.8-5.2 microM/l) than normal controls. When grouped according to sex, the mean serum F- concentration in males (3.05 +/- 1.04, range 1.8-5.2 microM/l) was significantly higher than females (2.38 +/- 1.08, range 0.8-5.2 microM/l). When patients were grouped according to age, it was observed that F- concentration was significantly higher in patients with age groups 21-70 (2.86 +/- 1.05) than those with age group 13-20 years (1.42 +/- 0.531). Thus F- concentration correlated with age and sex, being higher in males and above 20 years. Despite appreciable clearance of F- (39-90%) across the peritoneum, patients on CAPD showed higher serum F- concentration than those on HD (3.1 +/- 1.97 vs 2.5 +/- 1.137 microM/l). Of the total 39 patients on dialysis 39% had their serum F- concentration above 3.0 microM/l, posing the risk of renal osteodystrophy. |
| تدمد: | 1460-2385 0931-0509 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f419bc03780e2c9cb99d06eb2f3fea58 https://doi.org/10.1093/ndt/12.7.1420 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....f419bc03780e2c9cb99d06eb2f3fea58 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14602385 09310509 |
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