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Design and execution of a public randomization ceremony to enhance stakeholder engagement within a cluster randomized trial to improve tuberculosis diagnosis in Uganda

التفاصيل البيبلوغرافية
العنوان: Design and execution of a public randomization ceremony to enhance stakeholder engagement within a cluster randomized trial to improve tuberculosis diagnosis in Uganda
المؤلفون: Alex Kityamuwesi, Sara L. Ackerman, Achilles Katamba, Katherine Adams, Stavia Turyahabwe, Katherine Fielding, Tania F. Reza, Christopher Ojok, Mariam Nantale, Denis Oyuku, J. Lucian Davis, Sarah Nabwire, Adithya Cattamanchi, Annet Nakaweesa, Johnson Musinguzi, Margaret A. Handley, Diana Babirye, David Moore, David W. Dowdy, Talemwa Nalugwa
المصدر: Contemporary Clinical Trials Communications
Contemporary Clinical Trials Communications, Vol 22, Iss, Pp 100707-(2021)
بيانات النشر: Elsevier, 2021.
سنة النشر: 2021
مصطلحات موضوعية: Medicine (General), Randomization, Public randomization ceremony, media_common.quotation_subject, Clinical Trials and Supportive Activities, Stakeholder engagement, Impartiality, Article, 03 medical and health sciences, R5-920, Rare Diseases, 0302 clinical medicine, Tuberculosis diagnosis, Clinical Research, Trial Site, Cluster randomized trials, Tuberculosis, 030212 general & internal medicine, Cluster randomised controlled trial, media_common, Pharmacology, Medical education, Trial ethics, General Medicine, Ceremony, Comprehension, Good Health and Well Being, Infection, Psychology, 030217 neurology & neurosurgery
الوصف: Public randomization ceremonies have been proposed as a strategy to strengthen stakeholder engagement and address concerns and misconceptions associated with trial randomization. However, there are few published examples that describe how to conduct a public randomization ceremony with meaningful stakeholder engagement or how such ceremonies impact stakeholder perceptions about randomization and the randomization process. Cluster randomization for the GeneXpert Performance Evaluation for Linkage to Tuberculosis Care (XPEL-TB) trial was conducted at a public randomization ceremony attended by 70 stakeholders in Kampala, Uganda. Presentations given by the Acting Assistant Commissioner from the Uganda National Tuberculosis and Leprosy Programme and trial investigators emphasized how the trial aimed to further national TB goals, as well as how stakeholders contributed to the intervention design. The purpose and process of randomization were described using simple text and visuals. Randomization was an interactive activity that required participation of stakeholders from each trial site. A survey administered to stakeholders at the end of the ceremony suggested high comprehension of randomization (98%), trust in the randomization process (96%), and satisfaction with randomization outcomes (96%). Public randomization ceremonies should be considered more routinely to engage stakeholders in and address potential concerns about the fairness and impartiality of the randomization process for community-based trials.
وصف الملف: application/pdf
اللغة: English
تدمد: 2451-8654
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f45aea5c4e0374d41e46d4fb6bada028
http://europepmc.org/articles/PMC8131570
حقوق: OPEN
رقم الأكسشن: edsair.doi.dedup.....f45aea5c4e0374d41e46d4fb6bada028
قاعدة البيانات: OpenAIRE
الوصف
تدمد:24518654