Musculoskeletal Ultrasound in Monitoring Clinical Response to Treatment in Acute Symptomatic Psoriatic Dactylitis: Results from a Multicentre Prospective Observational Study
| العنوان: | Musculoskeletal Ultrasound in Monitoring Clinical Response to Treatment in Acute Symptomatic Psoriatic Dactylitis: Results from a Multicentre Prospective Observational Study |
|---|---|
| المؤلفون: | Niccolò Possemato, Rebecca McConnell, Raffaele Scarpa, Carlo Salvarani, Vittoria Bascherini, Nicolò Girolimetto, Pierluigi Macchioni, Giorgia Citriniti, Luisa Costa, Antonio Marchetta, Ilaria Tinazzi, Vincenzo Sabbatino, Francesco Caso, Rosario Peluso |
| المساهمون: | Girolimetto, Nicolò, Macchioni, Pierluigi, Possemato, Niccolò, Tinazzi, Ilaria, Bascherini, Vittoria, Citriniti, Giorgia, Mcconnell, Rebecca, Marchetta, Antonio, Peluso, Rosario, Sabbatino, Vincenzo, Salvarani, Carlo, Scarpa, Raffaele, Costa, Luisa, Caso, Francesco |
| المصدر: | Journal of Clinical Medicine Volume 9 Issue 10 Journal of Clinical Medicine, Vol 9, Iss 3127, p 3127 (2020) |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | dactylitis, psoriatic arthriti, dactyliti, lcsh:Medicine, flexor tenosynovitis, Article, Dactylitis, 03 medical and health sciences, Psoriatic arthritis, 0302 clinical medicine, Synovitis, medicine, 030212 general & internal medicine, Prospective cohort study, 030203 arthritis & rheumatology, psoriatic arthritis, soft tissue odema, business.industry, ultrasound, Ultrasound, lcsh:R, Soft tissue, General Medicine, medicine.disease, flexor tenosynoviti, Tendon, medicine.anatomical_structure, Observational study, business, Nuclear medicine |
| الوصف: | This observational and prospective study evaluated the clinical correlations of sonographic lesions in consecutive psoriatic arthritis (PsA) dactylitis cases. Eighty-three dactylitic digits were evaluated clinically and sonographically before treatment and at one-month (T1) and three-month (T3) follow-up. Clinical evaluation included the Leeds Dactylitis Index-basic (LDI-b) score and the visual analogue scales for pain (VAS-p) and functional impairment (VAS-FI). High-frequency ultrasound with grey scale (GS) and power Doppler (PD) assessed flexor tenosynovitis (FT), soft tissue oedema (STO), extensor tendon paratenonitis, and joint synovitis. There was a statistically significant correlation between the clinical parameters (VAS-p, VAS-FI, and LDI-b) and FT and STO at T1 and T3. We found statistically significant improvement in FT and STO for the cases with clinically meaningful treatment responses (p < 0.001). After a multiple conditional logistic regression analysis, the only variables that correlated with a T1 clinical response were the resolutions of PD FT (OR 15.66) and PD STO (OR 6.23), while the resolution of PD FT (OR 27.77) and of GS STO (OR 7.29) correlated with a T3 clinical response. The clinical improvements of active dactylitis are linked to the regression of sonographic evidence of extracapsular inflammation (particularly FT and STO). |
| وصف الملف: | application/pdf |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4e534fc07a49fadb265b0a192a530e0 https://hdl.handle.net/11380/1238689 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....f4e534fc07a49fadb265b0a192a530e0 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |