Fluid Therapy and Acute Respiratory Distress Syndrome
| العنوان: | Fluid Therapy and Acute Respiratory Distress Syndrome |
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| المؤلفون: | Jisoo Lee, Mitchell M. Levy, Keith Corl |
| المصدر: | Critical Care Clinics |
| بيانات النشر: | Elsevier Inc., 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Cardiac function curve, medicine.medical_specialty, ARDS, Conservative fluid management, Pulmonary Edema, Fluid management, Acute respiratory distress, Critical Care and Intensive Care Medicine, Article, Fluid therapy, medicine, Acute lung injury, Humans, Liberal fluid management, Prospective Studies, Deresuscitative fluid management, Intensive care medicine, Respiratory Distress Syndrome, Acute respiratory distress syndrome, business.industry, General Medicine, Pulmonary edema, medicine.disease, Phenotypes of acute respiratory distress syndrome, Clinical trial, Hyperinflammatory and hypoinflammatory acute respiratory distress syndrome, Fluid Therapy, business |
| الوصف: | The optimal fluid management for acute respiratory distress syndrome (ARDS) remains unknown. Liberal fluid management may improve cardiac function and end-organ perfusion, but may lead to increased pulmonary edema and inhibit gas exchange. Trials suggest that conservative fluid management leads to better clinical outcomes, although prospective randomized, controlled trials have not demonstrated mortality benefit. Recent discoveries suggest there is large heterogeneity in ARDS, and varying phenotypes of ARDS respond differently to fluid treatments. Future advances in management will require real-time assignment of ARDS phenotypes, which may facilitate inclusion into clinical trials by ARDS phenotype and guide development of targeted therapies. |
| اللغة: | English |
| تدمد: | 1557-8232 0749-0704 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f74df8dfae2fab70d04dea2800cd2765 http://europepmc.org/articles/PMC8449136 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....f74df8dfae2fab70d04dea2800cd2765 |
| قاعدة البيانات: | OpenAIRE |
Full Text via ClinicalKey | تدمد: | 15578232 07490704 |
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