التفاصيل البيبلوغرافية
العنوان:
Quinoline-4-acetamides as sPLA(2) inhibitors
المؤلفون:
Renxiao Wang , Luhua Lai , Ying Liu , Ying Gao , Yabing Feng
المصدر:
Bioorganicmedicinal chemistry letters . 11(13)
سنة النشر:
2001
مصطلحات موضوعية:
Magnetic Resonance Spectroscopy , medicine.drug_class , Stereochemistry , Clinical Biochemistry , Pharmaceutical Science , Carboxamide , Biochemistry , Chemical synthesis , Mass Spectrometry , Phospholipases A , chemistry.chemical_compound , Drug Discovery , Acetamides , medicine , Bioassay , Animals , Enzyme Inhibitors , Molecular Biology , Bicyclic molecule , biology , Molecular Structure , Organic Chemistry , Quinoline , Biological activity , Combinatorial chemistry , chemistry , Enzyme inhibitor , Proton NMR , biology.protein , Quinolines , Molecular Medicine
الوصف:
Quinoline-4-acetamides were designed as potential phospholipase A(2) inhibitors by structural based method and synthesized. The chemical structures of the obtained compounds were confirmed by elemental analyses, 1H NMR and MS. Preliminary bioassay study shows that quinoline-4-acetamides display certain inhibition to sPLA(2).
تدمد:
0960-894X
URL الوصول:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f79d77dff149e93f222bba2dae1f19af https://pubmed.ncbi.nlm.nih.gov/11425526
حقوق:
CLOSED
رقم الأكسشن:
edsair.doi.dedup.....f79d77dff149e93f222bba2dae1f19af
قاعدة البيانات:
OpenAIRE
