The adulterated XANAX pill: a fatal intoxication with etizolam and caffeine
| العنوان: | The adulterated XANAX pill: a fatal intoxication with etizolam and caffeine |
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| المؤلفون: | D. Rentsch, V. Kolbe, Andreas Büttner, D. Boy, B. Schmidt, R. Kegler |
| المصدر: | International Journal of Legal Medicine |
| بيانات النشر: | Springer Science and Business Media LLC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | medicine.drug_class, Poison control, Case Report, Pharmacology, Drug abuse, 01 natural sciences, Anxiolytic, Pathology and Forensic Medicine, Hypnotic, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Caffeine, medicine, 030216 legal & forensic medicine, Etizolam, Benzodiazepine, business.industry, 010401 analytical chemistry, 0104 chemical sciences, Alprazolam, chemistry, Sedative, business, Adulterated drugs, Fatal intoxication, medicine.drug |
| الوصف: | A 49-year old man was found dead at home next to a glass containing a dried, white, crystalline substance and near a bag containing pills with the imprint XANAX, the trade name of alprazolam. A comprehensive screening of material collected during the autopsy revealed the presence of etizolam and caffeine in lethal concentrations (0.77 μg/mL and 190 μg/mL) but no trace of alprazolam. Benzodiazepine analogue etizolam is rarely prescribed in Germany, and as a result there are not many reports about fatal cases. It has anxiolytic, hypnotic, sedative and muscle-relaxant properties and is used for the short-term treatment of anxiety and panic attacks. The purine alkaloid caffeine, conversely, is the most widely used central nervous system stimulant. The following report outlines potentially the first reported case of a lethal combination of the downer etizolam and the upper caffeine in medical literature. |
| تدمد: | 1437-1596 0937-9827 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9080ffba3f8c878d63ca782dd89ac8f https://doi.org/10.1007/s00414-020-02352-7 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....f9080ffba3f8c878d63ca782dd89ac8f |
| قاعدة البيانات: | OpenAIRE |
Find this article in full text from Springer Verlag. | تدمد: | 14371596 09379827 |
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