Pathology and biobanking
العنوان: | Pathology and biobanking |
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المؤلفون: | Muhammed Hasan Toper, Yasemin Şahin, Canan Kelten Talu, İbrahim Halil Erdoğdu |
المصدر: | Türk Patoloji Dergisi, Vol 36, Iss 2, Pp 093-108 (2020) |
بيانات النشر: | Federation of Turkish Pathology Societies, 2020. |
سنة النشر: | 2020 |
مصطلحات موضوعية: | human tissue biobank, Pathology, medicine.medical_specialty, media_common.quotation_subject, Pathology and Forensic Medicine, Resource (project management), Backup, Informed consent, lcsh:Pathology, Humans, Medicine, Confidentiality, Quality (business), quality control, pathology-centered biobank, Biological Specimen Banks, media_common, business.industry, Information technology, sustainability, Biobank, Optimal management, biobank, business, lcsh:RB1-214 |
الوصف: | Biobanks are units where high quality and long-term protection of biomaterials is maintained. This system, in which biological materials and data are systematically recorded and stored, is a unique resource for the study of the pathophysiology of disease, the development of diagnostic biomarkers, and working with human tissues for the potential discovery of targeted therapeutic agents. At this point, the pathology unit plays a unifying and complementary role between the clinical and core disciplines and offers optimal management of the patients� biomaterials for diagnostic and research projects. The aim of this article is to present general information with regard to a biobank constructed for the storage of tumor tissue and blood biospecimens. Ethical issues (informed consent, protection of confidentiality and privacy, and secondary use of biospecimens) and the information technology system (collection, systematic recording, backup and protection of clinical information) are important issues in biobanking. The selection of freezers to be used in storage (mechanical freezers, liquid-vapor nitrogen tanks), and if mechanical freezers are preferred the establishment of the relevant infrastructure and support team (such as additional power units for protection from power outages), the preservation of materials by aliquoting in different freezers, ensuring financing so as to afford the cost of the infrastructure, and implementation of all these dynamics while adhering to international guidelines are of the utmost importance. |
تدمد: | 1309-5730 1018-5615 |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f923cb0b7a8c3d1498f87cda7b43d2c8 https://doi.org/10.5146/tjpath.2020.01482 |
حقوق: | OPEN |
رقم الأكسشن: | edsair.doi.dedup.....f923cb0b7a8c3d1498f87cda7b43d2c8 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 13095730 10185615 |
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