RNA-Seq transcriptome data of human cells infected with influenza A/Puerto Rico/8/1934 (H1N1) virus
| العنوان: | RNA-Seq transcriptome data of human cells infected with influenza A/Puerto Rico/8/1934 (H1N1) virus |
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| المؤلفون: | Sergey Malanin, Andrey B. Komissarov, Tatiana V. Grigoryeva, D. V. Semenov, Mariia Sergeeva, Evgenii Zhuravlev, Rinat Amirkhanov, G. A. Stepanov |
| المصدر: | Data in Brief, Vol 33, Iss, Pp 106604-(2020) Data in Brief |
| بيانات النشر: | Elsevier, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | European Nucleotide Archive, RNA-Seq, Computational biology, Biology, medicine.disease_cause, lcsh:Computer applications to medicine. Medical informatics, Genome, Microbiology, Virus, Transcriptome, 03 medical and health sciences, 0302 clinical medicine, RefSeq, Influenza A virus, medicine, lcsh:Science (General), Gene, 030304 developmental biology, 0303 health sciences, Multidisciplinary, H1N1, Human cells, lcsh:R858-859.7, RNA-seq, 030217 neurology & neurosurgery, lcsh:Q1-390 |
| الوصف: | Human influenza remains a serious public health problem. This data article reports the transcriptome analysis data of human cell lines infected with influenza A/Puerto Rico/8/1934 (H1N1) virus. Mock-infected cells were included as controls. Human embryonic fibroblasts (MRC-5) and immortalized cell lines (A549, HEK293FT, WI-38 VA-13) were selected for RNA sequencing using Illumina NextSeq500 platform. Raw data were applied to the bioinformatic pipeline, which includes quality control with FastQC and MultiQC, adapter and quality trimming with Cutadapt, filtering to the genome of influenza A with STAR, transcript quantification with Salmon tool (GRCh38_RefSeq_Transcripts). Differential expressed genes were identified using R package DESeq2 with FDR-adjusted p-value < 0.001 and absolute value of log2(FC) > 1. Lists of differentially expressed genes is provided. The raw and processed RNA-seq data presented in this article were deposited to the European Nucleotide Archive via the ArrayExpress partner repository with the dataset accession number E-MTAB-9511 . |
| اللغة: | English |
| تدمد: | 2352-3409 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9528dd96344c9bbcd71efee6f54095c http://www.sciencedirect.com/science/article/pii/S2352340920314840 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....f9528dd96344c9bbcd71efee6f54095c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23523409 |
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