Integrating chemical and mechanical signals in neural crest cell migration
العنوان: | Integrating chemical and mechanical signals in neural crest cell migration |
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المؤلفون: | Adam Shellard, Roberto Mayor |
المصدر: | Current Opinion in Genetics & Development |
بيانات النشر: | Elsevier, 2019. |
سنة النشر: | 2019 |
مصطلحات موضوعية: | Population, Cancer metastasis, Biology, Mechanotransduction, Cellular, Article, Collective migration, 03 medical and health sciences, 0302 clinical medicine, Cranial neural crest, Cell Movement, Genetics, Animals, Humans, Mechanotransduction, education, Maxillofacial Development, Embryonic Stem Cells, 030304 developmental biology, 0303 health sciences, education.field_of_study, Skull, Neural crest, Embryonic stem cell, Neural Crest, embryonic structures, Neural crest cell migration, Neuroscience, 030217 neurology & neurosurgery, Developmental Biology |
الوصف: | Neural crest cells are a multipotent embryonic stem cell population that migrate large distances to contribute a variety of tissues. The cranial neural crest, which contribute to tissues of the face and skull, undergo collective migration whose movement has been likened to cancer metastasis. Over the last few years, a variety of mechanisms for the guidance of collective cranial neural crest cell migration have been described: mostly chemical, but more recently mechanical. Here we review these different mechanisms and attempt to integrate them to provide a unified model of collective cranial neural crest cell migration. |
اللغة: | English |
تدمد: | 1879-0380 0959-437X |
URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f97cbe05afdace14b601467db9a8c062 http://europepmc.org/articles/PMC6838680 |
حقوق: | OPEN |
رقم الأكسشن: | edsair.doi.dedup.....f97cbe05afdace14b601467db9a8c062 |
قاعدة البيانات: | OpenAIRE |
تدمد: | 18790380 0959437X |
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