Recurrence and colon cancer‐specific death in patients with large bowel obstruction requiring urgent operation: a competing risks analysis
| العنوان: | Recurrence and colon cancer‐specific death in patients with large bowel obstruction requiring urgent operation: a competing risks analysis |
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| المؤلفون: | Anil Keshava, Peter Stewart, Charles Chan, Michael Suen, Katie Adams, Owen F. Dent, Matthew J. F. X. Rickard, Pierre H. Chapuis |
| المصدر: | Colorectal Disease. 23:2604-2618 |
| بيانات النشر: | Wiley, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | medicine.medical_specialty, business.industry, Colorectal cancer, Incidence (epidemiology), Confounding, Hazard ratio, Gastroenterology, medicine.disease, Risk Assessment, Surgery, Large bowel obstruction, Colonic Neoplasms, medicine, Humans, In patient, Neoplasm Recurrence, Local, business, Competing risks analysis, Pathological, Colectomy, Intestinal Obstruction |
| الوصف: | AIM Clinical presentation with large bowel obstruction has been proposed as a predictor of poor long-term oncological outcomes after resection for colorectal cancer. This study examines the association between obstruction and recurrence and cancer-specific death after resection for colon cancer. METHOD Consecutive patients who underwent resection for colon cancer between 1995 and 2014 were drawn from a prospectively recorded hospital database with all surviving patients followed for at least 5 years. The outcomes of tumour recurrence and colon cancer-specific death were assessed by competing risks multivariable techniques with adjustment for potential clinical and pathological confounding variables. RESULTS Recurrence occurred in 271 of 1485 patients who had a potentially curative resection. In bivariate analysis, obstruction was significantly associated with recurrence [hazard ratio (HR) 2.23, CI 1.52-3.26, p |
| تدمد: | 1463-1318 1462-8910 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1453fe9bc15e7ee35cc29a3acfd077 https://doi.org/10.1111/codi.15807 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....fa1453fe9bc15e7ee35cc29a3acfd077 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14631318 14628910 |
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