Additional pharmacological activity of I‐modulia and generation of two newly designed extracts of Aquaphilus dolomiae culture for dermocosmetic actives
| العنوان: | Additional pharmacological activity of I‐modulia and generation of two newly designed extracts of Aquaphilus dolomiae culture for dermocosmetic actives |
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| المؤلفون: | M Maitre, K Ravard-Helffer, B Chol, F Farinole, T. Nguyen, F Lestienne, N Castex-Rizzi |
| المصدر: | Journal of the European Academy of Dermatology and Venereology. 34:27-29 |
| بيانات النشر: | Wiley, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Neurogenic inflammation, business.industry, Degranulation, Human skin, Biological activity, Cosmetics, Dermatology, Pharmacology, Neisseriaceae, In vitro, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Infectious Diseases, Humans, Medicine, Mast Cells, business, Neuroinflammation, Ex vivo, Skin, 030215 immunology, Explant culture |
| الوصف: | Aquaphilus dolomiae (AD) is a unique isolate from Avène Thermal Spring Water. I-Modulia, the first biotech extract from culture of AD, was used as immune modulator in Th2 inflammatory models. In this short publication, firstly we describe generation of two AD de novo extracts specifically designed for repairing and for neuroinflammation modulation activities which will be described, respectively, in two other articles in this supplement. Finally, for I-modulia, we describe new data on inhibition of human mast cell degranulation in vitro and its effect on substance P-induced neurogenic inflammation on ex vivo human skin explants. |
| تدمد: | 1468-3083 0926-9959 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6bc90b0d357cbf31836783e74a8541 https://doi.org/10.1111/jdv.16546 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....fb6bc90b0d357cbf31836783e74a8541 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14683083 09269959 |
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