Nitric Oxide Metabolites and Asymmetric Dimethylarginine Concentrations in Breast Milk
| العنوان: | Nitric Oxide Metabolites and Asymmetric Dimethylarginine Concentrations in Breast Milk |
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| المؤلفون: | Esin Koç, Ibrahim Murat Hirfanoglu, Yıldız Atalay, Taner Ozgurtas, Ebru Ergenekon, Ebru Kazanci, Ebru Ozcan, Canan Turkyilmaz, Hakan Ozturk, Esra Onal, Fatih Yesildal, Meltem Aksu |
| المصدر: | Gorm, Vol 23, Iss 1, Pp 41-44 (2017) |
| بيانات النشر: | Mebas Medikal Basin Yayin Ltd. Sti, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | medicine.medical_specialty, lcsh:Medicine, Breast milk, lcsh:Gynecology and obstetrics, Nitric oxide, chemistry.chemical_compound, fluids and secretions, 0404 agricultural biotechnology, Nitrate, Internal medicine, Medicine, Nitrite, lcsh:RG1-991, business.industry, lcsh:R, food and beverages, Gestational age, 04 agricultural and veterinary sciences, medicine.disease, 040401 food science, Endocrinology, chemistry, Necrotizing enterocolitis, Colostrum, business, Asymmetric dimethylarginine, Breast milk, Nitric oxide, Asymmetric dimethylarginine |
| الوصف: | Objective: Nitric oxide plays a preventive role in the development of necrotizing enterocolitis. Oral nitrite and nitrate intake has gained importance with the discovery of the conversion of nitrite to nitric oxide in acidic medium out of the synthesis of nitric oxide from L-arginine. Objective of this study was to examine the breast milk concentrations of nitric oxide and asymmetric dimethylarginine which is a competitive inhibitor of nitric oxide and to compare these concentrations in terms of gestational age and maturity of breast milk. Study Design: Forty-one women were included in the study. Milk samples were collected from 3 groups of mothers as term, late preterm and preterm on the postpartum days 3, 7 and 28. Results: When breast milk concentrations of nitric oxide were compared according to the postnatal day of the milk independently from gestational age; nitric oxide concentration was higher in the colostrum than in the transition milk and mature milk (p=0,035; p=0,001; respectively). For the comparison of asymmetric dimethylarginine concentrations among these groups and days; no statistically significant difference was observed in terms of gestational age and maturity of the milk (p=0.865, p=0.115; respectively). Conclusion: The highest nitric oxide concentration was found in the colostrum, suggesting that colostrum is a valuable food for newborns. Plasma concentrations of asymmetric dimethylarginine were negatively correlated with nitric oxide and did not show a correlation with breast milk, suggesting that asymmetric dimethylargininedoesn’t make nitric oxide inhibition in breast milk. |
| تدمد: | 2602-4918 1300-4751 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc6d4c4bbc9ddb02cecf8719ec25c834 https://doi.org/10.21613/gorm.2016.663 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....fc6d4c4bbc9ddb02cecf8719ec25c834 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 26024918 13004751 |
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