Environmental Echoes
| العنوان: | Environmental Echoes |
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| المؤلفون: | J L, Stanford, C A, Stanford, J M, Grange |
| المصدر: | Science Progress. 84:105-124 |
| بيانات النشر: | SAGE Publications, 2001. |
| سنة النشر: | 2001 |
| مصطلحات موضوعية: | 0209 industrial biotechnology, Multidisciplinary, Environmental Exposure, 02 engineering and technology, Infections, Biological Evolution, Autoimmune Diseases, Th2 Cells, 020303 mechanical engineering & transports, 020901 industrial engineering & automation, 0203 mechanical engineering, Neoplasms, Hypersensitivity, Humans, Immunocompetence |
| الوصف: | Allergy, auto immunity and cancer are becoming more prevalent in the developed world. One explanation might be that the immune system required to protect us from such problems is being inadequately trained, perhaps due to our increased separation from the environment which has shaped our mutating genes since we emerged from the primaeval ooze. Those infections which were the essential primers of our immunity are being prevented and action is needed to refocus the immune response without exposing us to the diseases of the past. In this paper we assess our place in relation to the environment and consider ways in which the situation can be redressed. There are considerable similarities between the immune system and human consciousness. Both enter the world in considerable ignorance of the events awaiting them, yet with the genetic ability, endowed by millennia of selection and evolution, to experience the world, to interpret and act on the experiences and to retain memory of the experiences. In both systems, maternal influences and early environmental encounters have profound effects on determining the patterns of subsequent responses. Ideally the ‘learned’ responses will benefit or protect the individual but inappropriate responses may lead to self damage. As the environment has altered irrevocably, attention must be paid to regulating the balance of immunological responsiveness to that expected of the normal immunological learning process. This should be possible by novel vaccination strategies. |
| تدمد: | 2047-7163 0036-8504 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc72ef44be81b9bda2e99e7253e01235 https://doi.org/10.3184/003685001783239014 |
| حقوق: | CLOSED |
| رقم الأكسشن: | edsair.doi.dedup.....fc72ef44be81b9bda2e99e7253e01235 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20477163 00368504 |
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