Effects of Some Acupoints (Du-14, Li-11, St-36, and Sp-6) on Serum TNF-α and hsCRP Levels in Healthy Young Subjects
| العنوان: | Effects of Some Acupoints (Du-14, Li-11, St-36, and Sp-6) on Serum TNF-α and hsCRP Levels in Healthy Young Subjects |
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| المؤلفون: | Kadir Yildirim, Fazile Hatipoglu Erdem, Filiz Alp, Saliha Karatay, Fatih Akçay |
| المصدر: | The Journal of Alternative and Complementary Medicine. 17:347-350 |
| بيانات النشر: | Mary Ann Liebert Inc, 2011. |
| سنة النشر: | 2011 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Acupuncture Therapy, Gastroenterology, Young Adult, Reference Values, Internal medicine, Healthy volunteers, Acupuncture, Humans, Medicine, Tumor Necrosis Factor-alpha, business.industry, Original Articles, Acupuncture treatment, Serum samples, Surgery, C-Reactive Protein, Complementary and alternative medicine, Needles, Reference values, Female, Sham acupuncture, Acupuncture needle, business, Acupuncture Points, After treatment |
| الوصف: | This study was performed to investigate the effect of immune-related acupuncture points on serum tumor necrosis factor-α (TNF-α) and high-sensitivity C-reactive protein (hsCRP) levels.Ninety (90) healthy volunteers (aged 20-30 years) were randomly assigned into five equal groups. Acupuncture needles were placed into single acupoints bilaterally in each group. The points were Da Zhui (Du-14), Qu Chi (Li-11), Zu San Li (St-36), San Yin Jiao (Sp-6) and a sham point, which is not an acupoint. Manual acupuncture treatment was performed in 6 sessions of 30 minutes each, 3 times per week for 2 weeks. Serum samples were obtained before and after the acupuncture treatments and the serum TNF-α and hsCRP levels were measured.The TNF-α values (mean ± standard deviation) in the Du-14, Li-11, St-36, Sp-6, and sham acupuncture groups at baseline were 37.63 ± 10.58, 37.36 ± 10.24, 33.83 ± 7.36, 35.73 ± 6.75, and 32.05 ± 5.66 pg/mL, respectively. After treatment, the mean TNF-α values were 35.89 ± 11.61, 34.80 ± 6.98, 35.89 ± 9.22, 33.30 ± 5.45, and 33.78 ± 5.98 pg/mL, respectively. In the serum TNF-α levels, no significant change was seen in any of the groups (p 0.05). The mean hsCRP values in the Du-14, Li-11, St-36, Sp-6, and sham acupuncture groups at baseline were 0.90 ± 0.77, 1.07 ± 1.35, 0.77 ± 0.54, 0.75 ± 0.54, and 0.94 ± 0.68 mg/L, respectively. After treatment, they were 1.09 ± 1.17, 0.84 ± 0.43, 0.74 ± 0.49, 0.80 ± 0.53, and 0.62 ± 0.44 mg/L, respectively. In the statistical analysis, it was found that hsCRP levels were significantly reduced in the sham acupuncture group (p 0.01). There was not any significant difference between acupuncture and sham groups in terms of serum TNF-α and hsCRP values (p 0.05).Acupoints, which are considered to have effects on the immune system, may not mediate the immune system via TNF-α, a known inflammatory cytokine, directly in healthy young individuals. However, the changes related to hsCRP values in the sham group need future confirmation studies. |
| تدمد: | 1557-7708 1075-5535 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd037a16d4c4d4029918b0cb7ed35c3d https://doi.org/10.1089/acm.2009.0461 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....fd037a16d4c4d4029918b0cb7ed35c3d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15577708 10755535 |
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