Motor Control Stabilisation Exercise for Patients with Non-Specific Low Back Pain: A Prospective Meta-Analysis with Multilevel Meta-Regressions on Intervention Effects
| العنوان: | Motor Control Stabilisation Exercise for Patients with Non-Specific Low Back Pain: A Prospective Meta-Analysis with Multilevel Meta-Regressions on Intervention Effects |
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| المؤلفون: | Heidrun Beck, Lutz Vogt, Adamantios Arampatzis, María Moreno Catalá, Daniel Niederer, Pia-Maria Wippert, Winfried Banzer, Christian Schneider, Michael Brenner-Fliesser, Claas Güthoff, Marcus Schiltenwolf, Ann-Christin Pfeifer, Petra Platen, Frank Mayer, Alexander Hönning, Thore Haag, Tilman Engel, Katharina Trompeter |
| المصدر: | Journal of Clinical Medicine Volume 9 Issue 9 Journal of Clinical Medicine, Vol 9, Iss 3058, p 3058 (2020) |
| بيانات النشر: | Multidisciplinary Digital Publishing Institute, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | unspecific low back pain, medicine.medical_specialty, lcsh:Medicine, Intervention effect, lumbago, Article, law.invention, nonspecific, 03 medical and health sciences, 0302 clinical medicine, Non specific, Randomized controlled trial, law, LBP, Medicine, motor control exercise, 030212 general & internal medicine, Lead (electronics), sensorimotor, exercise, business.industry, lcsh:R, Motor control, General Medicine, lumbalgia, Random effects model, Low back pain, stabilization, meta-analysis, Meta-analysis, Physical therapy, chronic low back pain, medicine.symptom, business, 030217 neurology & neurosurgery |
| الوصف: | Low-to-moderate quality meta-analytic evidence shows that motor control stabilisation exercise (MCE) is an effective treatment of non-specific low back pain. A possible approach to overcome the weaknesses of traditional meta-analyses would be that of a prospective meta-analyses. The aim of the present analysis was to generate high-quality evidence to support the view that motor control stabilisation exercises (MCE) lead to a reduction in pain intensity and disability in non-specific low back pain patients when compared to a control group. In this prospective meta-analysis and sensitivity multilevel meta-regression within the MiSpEx-Network, 18 randomized controlled study arms were included. Participants with non-specific low back pain were allocated to an intervention (individualized MCE, 12 weeks) or a control group (no additive exercise intervention). From each study site/arm, outcomes at baseline, 3 weeks, 12 weeks, and 6 months were pooled. The outcomes were current pain (NRS or VAS, 11 points scale), characteristic pain intensity, and subjective disability. A random effects meta-analysis model for continuous outcomes to display standardized mean differences between intervention and control was performed, followed by sensitivity multilevel meta-regressions. Overall, 2391 patients were randomized 1976 (3 weeks, short-term), 1740 (12 weeks, intermediate), and 1560 (6 months, sustainability) participants were included in the meta-analyses. In the short-term, intermediate and sustainability, moderate-to-high quality evidence indicated that MCE has a larger effect on current pain (SMD = &minus 0.15, &minus 0.19), pain intensity (SMD = &minus 0.19, &minus 0.26, &minus 0.26) and disability (SMD = &minus 0.27, &minus 0.25) compared with no exercise intervention. Low-quality evidence suggested that those patients with comparably intermediate current pain and older patients may profit the most from MCE. Motor control stabilisation exercise is an effective treatment for non-specific low back pain. Sub-clinical intermediate pain and middle-aged patients may profit the most from this intervention. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2077-0383 |
| DOI: | 10.3390/jcm9093058 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fddea0036876dfde261447f37165a887 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....fddea0036876dfde261447f37165a887 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20770383 |
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| DOI: | 10.3390/jcm9093058 |