The Impact of the Meningococcal Serogroup C Conjugate Vaccine in Canada Between 2002 and 2012
| العنوان: | The Impact of the Meningococcal Serogroup C Conjugate Vaccine in Canada Between 2002 and 2012 |
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| المؤلفون: | Robert F. Morris, David M. Moore, Ben Tan, D. Scheifele, Halperin S, R. Tsang, Laura Sauve, Scott A. Halperin, Vaudry W, Julie A. Bettinger, Taj Jadavji, Marc H. Lebel, Manish Sadarangani, N. Bridger, Wendy Vaudry, Nicole Le Saux, K. Top, David W. Scheifele, Joanne Embree, Raymond S. W. Tsang, N Le Saux, Barbara Law, Otto G. Vanderkooi, Dat Tran, Lee Ford-Jones, Pierre Déry, J. Bettinger |
| المصدر: | Clinical Infectious Diseases. 59:1208-1215 |
| بيانات النشر: | Oxford University Press (OUP), 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Microbiology (medical), Pediatrics, medicine.medical_specialty, education.field_of_study, business.industry, Incidence (epidemiology), Neisseria meningitidis, Population, Meningococcal disease, medicine.disease, medicine.disease_cause, Monitoring program, Herd immunity, Infectious Diseases, Conjugate vaccine, medicine, business, education, Meningitis |
| الوصف: | BACKGROUND: Before 2001, the incidence of invasive meningococcal disease (IMD) in Canada was 1.0 per 100 000 per year, with 40% of cases caused by serogroup C organisms. During 2001-2005 all provinces introduced the meningococcal serogroup C conjugate vaccine (MCCV) into their routine infant immunization schedule. METHODS: Active, prospective, population-based surveillance of IMD in children and adults was conducted by the Canadian Immunization Monitoring Program, ACTive (IMPACT) during 2002-2012. Inclusion criteria were admission to hospital and identification of Neisseria meningitidis from a sterile site. Incidence was estimated using population census data from Statistics Canada. RESULTS: Prior to MCCV introduction, serogroup C disease incidence was 0.07-0.25 per 100 000 per year depending on the province. Following vaccine introduction, serogroup C disease decreased to |
| تدمد: | 1537-6591 1058-4838 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff0a16ec1c8125dab448b4660361c736 https://doi.org/10.1093/cid/ciu597 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....ff0a16ec1c8125dab448b4660361c736 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15376591 10584838 |
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