Lutein intake at the age of 1 year and cardiometabolic health at the age of 6 years: the Generation R Study
| العنوان: | Lutein intake at the age of 1 year and cardiometabolic health at the age of 6 years: the Generation R Study |
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| المؤلفون: | Albert Hofman, Elisabeth T.M. Leermakers, Oscar H. Franco, Jessica C. Kiefte-de Jong, Vincent W. V. Jaddoe |
| المساهمون: | Epidemiology, Erasmus MC other |
| المصدر: | British Journal of Nutrition, 114(6), 970-978. Cambridge University Press British Journal of Nutrition, 114(6), 970-978 |
| بيانات النشر: | Cambridge University Press (CUP), 2015. |
| سنة النشر: | 2015 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Epidemiology, Population, Medicine (miscellaneous), Physiology, Blood lipids, Body composition, Body fat percentage, Antioxidants, Cohort Studies, Child Development, Risk Factors, Internal medicine, medicine, Humans, Longitudinal Studies, Prospective Studies, Infant Nutritional Physiological Phenomena, education, Prospective cohort study, Children, Netherlands, Metabolic Syndrome, education.field_of_study, Nutrition and Dietetics, business.industry, Cardiometabolic health, Lutein, Infant, food and beverages, Anthropometry, Hospitals, Pediatric, Nutrition Surveys, beta Carotene, Carotenoids, Diet, Endocrinology, Cardiovascular Diseases, Lean body mass, Female, Generation R, Energy Intake, business, Cohort study |
| الوصف: | Lutein is a carotenoid with strong antioxidant properties. Previous studies in adults suggest a beneficial role of lutein on cardiometabolic health. However, it is unknown whether this relation also exists in children; therefore, we aimed to assess the relation between lutein intake at 13 months of age and cardiometabolic outcomes at the age of 6 years. We included 2044 Dutch children participating in a population-based prospective cohort study. Diet was measured at 13 months of age with an FFQ. Lutein intake was standardised for energy and β-carotene intake. Blood pressure, anthropometrics, serum lipids and insulin were measured at the age of 6 years. Dual-energy X-ray absorptiometry was performed to measure total and regional fat and lean mass. A continuous cardiometabolic risk factor score was created, including the components body fat percentage, blood pressure, insulin, HDL-cholesterol and TAG. Age- and sex-specific standard deviation scores were created for all outcomes. Multivariable linear regression was performed, including socio-demographic and lifestyle variables. Median (energy-standardised) lutein intake was 1317 mcg/d (95 % range 87, 6069 mcg/d). There were no consistent associations between lutein intake at 13 months and anthropometrics and body composition measures at 6 years of age. In addition, lutein intake was not associated with a continuous cardiometabolic risk factor score, nor was it associated with any of the individual components of the cardiometabolic risk factor score. Results from this large population-based prospective cohort study do not support the hypothesis that lutein intake early in life has a beneficial role for later cardiometabolic health. |
| تدمد: | 1475-2662 0007-1145 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff228db267b1436162da6ed2a547200b https://doi.org/10.1017/s0007114515002779 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....ff228db267b1436162da6ed2a547200b |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14752662 00071145 |
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