Patatin-like lipolytic acyl hydrolases and galactolipid metabolism in marine diatoms of the genus Pseudo-nitzschia
| العنوان: | Patatin-like lipolytic acyl hydrolases and galactolipid metabolism in marine diatoms of the genus Pseudo-nitzschia |
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| المؤلفون: | Maria Grazia Adelfi (a, Rosa Maria Vitale (a), Giuliana d'Ippolito (a), Genoveffa Nuzzo (a), Carmela Gallo (a), Pietro Amodeo (a ), Emiliano Manzo (a), Dario Pagano (a), Simone Landi (a), Gianluca Picariello (c), Maria Immacolata Ferrante (b), Angelo Fontana (a) |
| المساهمون: | Adelfi, M. G., Vitale, R. M., D'Ippolito, G., Nuzzo, G., Gallo, C., Amodeo, P., Manzo, E., Pagano, D., Landi, S., Picariello, G., Ferrante, M. I., Fontana, A. |
| المصدر: | Biochimica and biophysica acta. Molecular and cell biology of lipids 1864 (2019): 181–190. doi:10.1016/j.bbalip.2018.11.008 info:cnr-pdr/source/autori:Adelfi, Maria Grazia; Vitale, Rosa Maria; d'Ippolito, Giuliana; Nuzzo, Genoveffa; Gallo, Carmela; Amodeo, Pietro; Manzo, Emiliano; Pagano, Dario; Landi, Simone; Picariello, Gianluca; Ferrante, Maria Immacolata; Fontana, Angelo/titolo:Patatin-like lipolytic acyl hydrolases and galactolipid metabolism in marine diatoms of the genus Pseudo-nitzschia/doi:10.1016%2Fj.bbalip.2018.11.008/rivista:Biochimica and biophysica acta. Molecular and cell biology of lipids/anno:2019/pagina_da:181/pagina_a:190/intervallo_pagine:181–190/volume:1864 Biochimica and biophysica acta. Molecular and cell biology of lipids (2018): 181–190. doi:10.1016/j.bbalip.2018.11.008 info:cnr-pdr/source/autori:Maria Grazia Adelfi (a, b), Rosa Maria Vitale (a), Giuliana d'Ippolito (a), Genoveffa Nuzzo (a), Carmela Gallo (a), Pietro Amodeo (a ), Emiliano Manzo (a), Dario Pagano (a), Simone Landi (a), Gianluca Picariello (c), Maria Immacolata Ferrante (b), Angelo Fontana (a)/titolo:Patatin-like lipolytic acyl hydrolases and galactolipid metabolism in marine diatoms of the genus Pseudo-nitzschia/doi:10.1016%2Fj.bbalip.2018.11.008/rivista:Biochimica and biophysica acta. Molecular and cell biology of lipids/anno:2018/pagina_da:181/pagina_a:190/intervallo_pagine:181–190/volume |
| بيانات النشر: | Elsevier, New York ;, Paesi Bassi, 2019. |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | 0106 biological sciences, 0301 basic medicine, Hydrolases, Lipolysis, Lipoxygenase, Hydrolase, Glycolipid, 01 natural sciences, Chloroplast, 03 medical and health sciences, Galactolipase, Galactolipid, Microalgae, Oxylipins, Plastid, Molecular Biology, Diatoms, chemistry.chemical_classification, biology, Galactolipids, fungi, Lipid metabolism, Diatom, Lipoxygenase pathway, Patatin, Cell Biology, Lipidmetabolism, Lipase, biology.organism_classification, Lipolysi, Phospholipid, 030104 developmental biology, chemistry, Biochemistry, Eicosapentaenoic Acid, biology.protein, Fatty Acids, Unsaturated, 010606 plant biology & botany, Polyunsaturated fatty acid |
| الوصف: | Diatoms are eukaryotic microalgae that play a pivotal role in biological and geochemical marine cycles. These microorganisms are at the basis of the trophic chain and their lipids are essential components (e.g. eicosapentaenoic acid, EPA) of aquatic food webs. Galactolipids are the primary lipid components of plastid membranes and form the largest lipid family of diatoms. As source of polyunsaturated fatty acids (PUFAs), these compounds are also involved in the synthesis of lipoxygenase (LOX) products such as non-volatile oxylipins and polyunsaturated aldehydes. Here, we report the first identification of two genes, namely PmLAH1 and PaLAH1, coding for lipolytic enzymes in two diatoms of the genus Pseudo-nitzschia. Functional and modeling studies evidence a patatin-like domain endowed with galactolipase and phospholipase activity at the C-terminus of both proteins. Homologues of Pseudo-nitzschia LAH1 genes were retrieved in other diatom species so far sequenced in agreement with conservation of the functional role of these proteins within the lineage. |
| اللغة: | English |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7355880dbdded548d42a132a17d33a https://publications.cnr.it/doc/440474 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.doi.dedup.....ff7355880dbdded548d42a132a17d33a |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |