التفاصيل البيبلوغرافية
| العنوان: |
Countercurrently Operated Reactive Extractor with an Additively Manufactured Enzyme Carrier Structure |
| المصدر: |
Organic process research & development. |
| سنة النشر: |
2020 |
| مصطلحات موضوعية: |
biocatalysis, additively manufactured enzyme carriers, periodic open-cell structures (POCS), in situ product removal (ISPR), rapid prototyping |
| الوصف: |
Copyright © 2020 American Chemical Society. Precisely designed structures inserted in hybrid reactors can be used to control multiphase hydrodynamics and to act as a catalyst carrier simultaneously. While numerical simulations with computational fluid dynamics have limitations regarding the complex interactions in multiphase flows, performing experiments using rapid prototyping (RP) offers the possibility of a fast fabrication and verification of tailor-made structures for specific flow characteristics, efficient mass transport, and high conversion rates. In the presented work, the development of a countercurrently operated additively manufactured reactor for the decarboxylation of ferulic acid to 2-methoxy-4-vinylphenol (MVP) along in situ extraction with n-heptane is shown. Here, the use and optimization of periodic open-cell structures (POCSs) as a carrier for the enzyme phenolic acid decarboxylase and a distributor for the extraction phase are targeted. By RP of transparent structures and their examination concerning the induced flow characteristics of colored heptane, a structure could be optimized for the specific reaction system. The additive manufacturing of POCSs and their application in a hybrid countercurrently operated reactor enabled the conversion of FA and a low concentration of the competitively inhibiting product MVP in the reaction phase via efficient in situ extraction via the dispersed heptane phase. |
| تدمد: |
1083-6160 |
| URL الوصول: |
https://explore.openaire.eu/search/publication?articleId=dris___01170::dee1655bf6c9a186fe3001c6a1d0c8fd
https://hdl.handle.net/11420/7726 |
| حقوق: |
CLOSED |
| رقم الأكسشن: |
edsair.dris...01170..dee1655bf6c9a186fe3001c6a1d0c8fd |
| قاعدة البيانات: |
OpenAIRE |
Find this issue from the American Chemical Society