التفاصيل البيبلوغرافية
| العنوان: |
Prognostic role of microRNAs in breast cancer: A systematic review |
| المؤلفون: |
Zografos, E. Zagouri, F. Kalapanida, D. Zakopoulou, R. Kyriazoglou, A. Apostolidou, K. Gazouli, M. Dimopoulos, M.-A. |
| سنة النشر: |
2019 |
| الوصف: |
MicroRNAs (miRNAs) have been found to play an important role in breast cancer, functioning either as potential oncogenes or tumor suppressor genes, but their role in the prognosis of patients remains unclear. The aim of the present review study is to highlight recent preclinical and clinical studies performed on both circulating and tissue-specific miRNAs and their potential role as prognostic markers in breast cancer. We systematically searched the PubMed database to explore the prognostic value of miRNAs in breast cancer. After performing the literature search and review, 117 eligible studies were identified. We found that 110 aberrantly expressed miRNAs have been associated with prognosis in breast cancer. In conclusion, the collective data presented in this review indicate that miRNAs could serve as novel prognostic tools in breast cancer, while the clinical application of these findings has yet to be verified. Copyright: © Zografos et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0). |
| اللغة: |
English |
| URL الوصول: |
https://explore.openaire.eu/search/publication?articleId=od______2127::b2dfb04983af651723bcdf45170b14bb
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3106394 |
| حقوق: |
OPEN |
| رقم الأكسشن: |
edsair.od......2127..b2dfb04983af651723bcdf45170b14bb |
| قاعدة البيانات: |
OpenAIRE |
