Correlation between metabolic syndrome and its components with psoriasis severity
| العنوان: | Correlation between metabolic syndrome and its components with psoriasis severity |
|---|---|
| المؤلفون: | Levakov, Olivera |
| المساهمون: | Gajinov, Zorica, Matić, Milan, Vujanović, Ljuba, Ivkov, Simić Milana, Ilinčić, Branislava, Jovanović, Dragan |
| المصدر: | CRIS UNS |
| بيانات النشر: | Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2023. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Psoriasis, Arthritis, Psoriatic, Metabolic Syndrome, Insulin Resistance, Patient Acuity, Demography, Waist Circumference, Hyperglycemia, Cholesterol, HDL, psorijaza, psorijatski artritis, metabolički sindrom, insulinska rezistencija, težina kliničke slike, demografija, obim struka, hiperglikemija, HDL holesterol |
| الوصف: | Uvod: Poslednjih godina se sve više usvaja koncept psorijaze kao sistemske bolesti zbog njene povezanosti sa brojnim komorbiditetima, prvenstveno sa metaboličkim sindromom i kardiovaskularnim bolestima. Mali broj radova se bavi korelacijom prevalencije metaboličkog sindroma i svih njegovih pojedinačnih komponenti sa težinom kliničke slike psorijaze, raširenošću promena i prisustvom psorijatskog artritisa, a rezultati su do sada oprečni. Ciljevi: Utvrditi da li postoji povezanost između težine kliničke slike psorijaze (PsO) i udruženosti sa psorijatskim artritisom (PsA) i prevalencije metaboličkog sindroma (MetS) i njegovih komponenti. Evaluirati da li su težina kliničke slike i PsA prediktori za razvoj insulinske rezistencije (IR), nezavisno od prisustva MetS-a. Utvrditi povezanost metaboličkog sindroma i njegovih komponenti sa nezavisnim varijablama, demografskim karakteristikama ispitanika i kliničkim karakteristikama plak psorijaze. Materijal i metode: Ova prospektivna, opservaciono deskriptivna studija je sprovedena na Klinici za kožno-venerične bolesti u Univerzitetskom kliničkom centru Vojvodine. U studiju je uključeno 105 pacijenata sa hroničnom plak psorijazom koji su podeljeni u tri grupe. Grupa sa lakšim oblikom psorijaze (Psoriasis area severity index-PASI Introduction: In recent years, the concept of psoriasis as a systemic disease has been increasingly adopted due to its association with numerous comorbidities, primarily metabolic syndrome and cardiovascular disease. A small number of studies dealt with the association of metabolic syndrome, and its individual components prevalence with the severity of the psoriasis and PsA presence, and the results so far are contradictory. Aims: To determine whether there is an association of metabolic syndrome (MetS) and its components with psoriasis severity and psoriatic arthritis (PsA) presence. To evaluate whether psoriasis severity and association with PsA are predictors of insulin resistance, independent of MetS presence. To determine the association of metabolic syndrome and its components with independent variables, demographic characteristics of subjects, and clinical characteristics of plaque psoriasis. Materials and methods: This prospective, observational descriptive cross-sectional study was conducted at Dermatovenereological clinic in University Clinical Centre of Vojvodina, and included total of 105 psoriasis patients divided into 3 groups. Group with mild psoriasis (Psoriasis Area Severity Index - PASI score |
| اللغة: | Serbian |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=od______2987::139594c04a37f11b118a47968f3977c9 https://www.cris.uns.ac.rs/DownloadFileServlet/Disertacija166505570273338.pdf?controlNumber=(BISIS)120898&fileName=166505570273338.pdf&id=20655&source=OpenAIRE&language=en |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.od......2987..139594c04a37f11b118a47968f3977c9 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |