Titration of sevoflurane using the bispectral index in pediatric anesthesia. Premedication effects on emergence time and consumption of inhalational anesthetic
| العنوان: | Titration of sevoflurane using the bispectral index in pediatric anesthesia. Premedication effects on emergence time and consumption of inhalational anesthetic |
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| المؤلفون: | Ganem, Eliana Marisa [UNESP], Módolo, Norma Sueli Pinheiro [UNESP], Vianna, Pedro Thadeu Galvão [UNESP], Castiglia, Yara Marcondes Machado [UNESP] |
| المساهمون: | Universidade Estadual Paulista (Unesp) |
| المصدر: | Scopus Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| سنة النشر: | 2000 |
| مصطلحات موضوعية: | premedication, clonidine, midazolam [PREMEDICATION], patient monitoring, atracurium, sevoflurane, electroencephalography, bispectral index [MONITORING], alfentanil, hemodynamics, sevoflurane [ANESTHETICS, Volatile], male, dose response, heart rate, controlled study, human, clonidine, anesthesia induction, child, clinical article, nitrous oxide, propofol, drug effect, titrimetry, female, midazolam, anesthetic recovery, electroencephalography, pediatric anesthesia |
| الوصف: | Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:19:52Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:45:13Z : No. of bitstreams: 1 2-s2.0-0034085892.pdf: 114238 bytes, checksum: c02cb431f7e3bf3142f86d6d872a1e2d (MD5) Made available in DSpace on 2014-05-27T11:19:52Z (GMT). No. of bitstreams: 0 Previous issue date: 2000-01-01 Background and Objectives - Sevoflurane is an inhalational anesthetic drug with low blood/gas solubility providing fast anesthesia induction and emergence. Its ability to maintain cardiovascular stability makes it ideal for pediatric anesthesia. The aim of this study was to evaluate hemodynamic stability, consumption of inhalational anesthetics and emergence time in children with and without premedication (midazolam or clonidine) anesthetized with sevoflurane titrated according to BIS monitoring. Methods - Participated in this study 30 patients aged 2 to 12 years, physical status ASA I, undergoing elective surgeries who were divided into 3 groups: G1 - without premedication, G2 - 0.5 mg.kg-1 oral midazolam, G3 - 4 μg.kg-1 oral clonidine 60 minutes before surgery. All patients received 30 μg.kg-1 alfentanil, 3 mg.kg-1 propofol, 0.5 mg.kg-1 atracurium, sevoflurane in different concentrations monitored by BIS (values close to 60) and N2O in a non rebreathing system. Systolic and diastolic blood pressure, heart rate, expired sevoflurane concentration (EC), sevoflurane consumption (ml.min-1) and emergence time were evaluated. Emergence time was defined as time elapsed between the end of anesthesia and patients' spontaneous movements trying to extubate themselves, crying and opening eyes and mouth. Results - There were no differences among groups as to systolic and diastolic blood pressure, EC, sevoflurane consumption and emergence time. Heart rate was lower in G3 group. Conclusions - Sevoflurane has provided hemodynamic stability. Premedication with clonidine and midazolam did not influence emergence time, inhaled anesthetic consumption or maintenance of anesthesia with sevoflurane. Anesthesia duration has also not influenced emergence time. Hypnosis monitoring was important for balancing anesthetic levels and this might have been responsible for the similarity of emergence times for all studied groups. Depto. de Anestesiologia da FMB UNESP, Distrito de Rubiao Junior, 18618-970 Botucatu, SP Depto. de Anestesiologia da FMB UNESP, Distrito de Rubiao Junior, 18618-970 Botucatu, SP |
| اللغة: | Portuguese |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=od______3056::47f9d0e24cbf07be78864e22f95adfd9 http://www.sba.com.br/arquivos/revista/rba/mai00197.pdf |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.od......3056..47f9d0e24cbf07be78864e22f95adfd9 |
| قاعدة البيانات: | OpenAIRE |
| الوصف غير متاح. |