Effect of Blood Donation Mediated Volume Reduction on Right Ventricular Function Parameters in Healthy Subjects

التفاصيل البيبلوغرافية
العنوان: Effect of Blood Donation Mediated Volume Reduction on Right Ventricular Function Parameters in Healthy Subjects
المؤلفون: Kucukdurmaz, Zekeriya, Karapinar, Hekim, Karavelioglu, Yusuf, Acar, Goksel, Gul, Ibrahim, Emiroglu, Mehmet Yunus, Bulut, Mustafa, Esen, Ali Metin
المساهمون: [Kucukdurmaz, Zekeriya -- Karapinar, Hekim -- Gul, Ibrahim] Cumhuriyet Univ, Dept Cardiol, Sch Med, Sivas, Turkey -- [Karapinar, Hekim -- Karavelioglu, Yusuf -- Acar, Goksel -- Emiroglu, Mehmet Yunus -- Bulut, Mustafa -- Esen, Ali Metin] Kartal Kosuyolu High Specialty Educ & Res Hosp, Dept Cardiol, Istanbul, Turkey
بيانات النشر: WILEY-BLACKWELL, 2012.
سنة النشر: 2012
مصطلحات موضوعية: systolic function, tissue Doppler, tricuspid annular plane systolic excursion, myocardial performance index, right heart
الوصف: WOS: 000302540700020
PubMed ID: 22324433
Purpose: We aimed to investigate the effect of controlled and limited volume change by the blood donation model to the right ventricular (RV) function via different echocardiographic parameters in healthy adults. Methods: Study population was composed of 71 healthy subjects who were volunteers for blood donation and evaluated before and after 450 mL blood donation. Pulsed-wave Doppler of the RV inflow and tissue Doppler of tricuspid lateral annulus, and tricuspid annular plane systolic excursion (TAPSE) were assessed. Results: E velocity of inflow decreased significantly (67.6 +/- 15.9 vs 60.9 +/- 12.2, P = 0.006). S and A velocities did not change (15.3 +/- 3.2 vs 15.2 +/- 2.5 cm/s, P = NS; 14.1 +/- 3.3 vs 13.4 +/- 3.1 cm/s, P = NS, respectively) but E showed significant decrease (13.7 +/- 2.9 vs 12.2 +/- 3.2 cm/s, P = 0.011). E/A ratio and E/E ratio were found to be unchanged (1.0 +/- 0.3 vs 1.0 +/- 0.4, P = NS; 5.1 +/- 2 vs 5.3 +/- 2, P = NS, respectively). Myocardial performance index (MPI) was found to be increased but ejection time obtained from the tricuspid annulus did not change (0.50 +/- 0.13 vs 0.54 +/- 0.11, P = 0.040; 243 +/- 37 vs 240 +/- 27, P = NS, respectively). Isovolumetric relaxation and contraction times showed difference close to the significance limit (56 +/- 19 vs 64 +/- 23 ms, P = 0.055; 61 +/- 16 vs 67 +/- 16 ms, P = 0.062, respectively). TAPSE decreased significantly (2.62 +/- 0.29 vs 2.41 +/- 0.27 mm, P = 0.005). Conclusion: E velocity and TAPSE were sensitive to a volume reduction as little as 450 mL in healthy subjects. MPI index of the tricuspid annulus is less sensitive than E and TAPSE but need much care under changing volume state. However S and A velocity and E/A ratio were found to be resistant to the effects of volume depletion. (Echocardiography 2012;29:451-454)
اللغة: English
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3104::9203f7deeec67f9495150c72d7e48fdd
https://hdl.handle.net/20.500.12418/9189
حقوق: CLOSED
رقم الأكسشن: edsair.od......3104..9203f7deeec67f9495150c72d7e48fdd
قاعدة البيانات: OpenAIRE