The invention relates to compds. of formula I, pharmaceutical compns. comprising these compds., their use in the treatment of kinetoplastid infections and their prepn. Compds. of formula I, wherein A is absent, O, S, etc.; B is absent, (CH2)n and CO; Z is absent, CO, SO2, etc.; X and Y are independently H, halo, C1-6 alkyl, etc.; m and n are 1 or 2 wherein at least one must be 1; p is 0 , 1 and 2; Het is 1H-imidazole, 4H-1,2,4-triazole, oxazole, etc.; R1 is naphthalen-2-yl, 2-methoxyquinolin-3-yl, pryimdin-5-yl, etc.; R2 is H, C6-10 aryl, C3-15 heterocyclyl, etc.; and pharmaceutically acceptable salts, tautomers and stereoisomers thereof, are claimed. Compd. II.bul.TFA was prepd. using a multistep procedure (procedure given). Compds. of the invention were tested for their inhibitory activity against T. brucei (data given).