Magini G, Frigerio M, Farsad M, Serra C, Colecchia A, Jovine E, Vivarelli M, Feletti V, Golfieri R, Lodi F, Franchi R, Fanti S, Bernardi M, Trevisani F
Background and Aims: We evaluated the usefulness of Positon Emission Tomography (PET) with two tracers, 11C-Acetate and 18FFluorodeoxyglucose (FDG), for differentiating focal nodular hyperplasia (FNH), that is managed conservatively, from hepatic adenoma (HA) that needs to be resected. Methods: We prospectively enrolled 30 patients with known or suspected FNH or HA. The diagnostic work-up included Doppler ultrasonography (US), contrast enhanced computed tomography (CT) and/or magnetic resonance imaging (MRI). Fine needle biopsy (FNB) was performed if imaging study was inconclusive. All patients underwent double tracer PET with a single day protocol. The images were acquired with a PET-CT tomograph to obtain image fusion. The tracer uptake was evaluated using the maximum standardized uptake value (SUVmax). The target to background (T/B) ratio was also calculated. Lesions
