Endoscopic retrograde cholangiopancreatography (ERCP) is an irreplaceable measure with minimally invasive diagnosis and treatment of endoscopy for biliary and pancreatic diseases, but the related complications associated with ERCP are the highest among the endoscopic procedures. Post-ERCP pancreatitis (PEP) is one of the most common complications with life-threatening in severe cases. Early active prevention can effectively reduce the incidence of post-ERCP pancreatitis. At present, measures including preoperative rectal non-steroidal anti-inflammatory drugs and prophylactic pancreatic stent placement, have definite effective strategy in clinic. Aggressive hydration with lactated Ringer's solution is also a safe and effective way to prevent PEP.经内镜逆行性胰胆管造影术(endoscopic retrograde cholangiopancreatography，ERCP)是胆胰疾病内镜微创诊治的重要手段，但与其他内镜操作相比，ERCP术后相关的并发症最高。ERCP术后胰腺炎(post-ERCP pancreatitis，PEP)是其中最常见的并发症，严重时可能危及生命。积极的早期预防可以有效降低PEP的发生率。目前，在临床上有明确效果的措施包括术前非甾体抗炎药纳肛和预防性胰管支架置入，使用乳酸林格氏液积极的水化也是预防PEP安全有效的方法。.
