Parkinson's disease (PD), also known as paralysis tremor, is a chronic disease of the central nervous system. It has been reported that hepatocyte nuclear factor 4 alpha (HNF4A) is upregulated in PD, but its specific function has not been well explored.We established an in vitro PD model in SH-SY5Y cells stimulated with 1-methyl-4-phenylpyridinium (MPPThe results revealed that depletion of HNF4A suppressed cell cytotoxicity and apoptosis caused by MPPOur study first proved LINC00667, miR-34c-5p, and HNF4A constructed a positive feedback loop in MPP
