Cancer of the paranasal sinuses and nasal cavity is an uncommon disease accounting for less than 0.2% of all malignancies. Lymphoma of the paranasal sinuses is a rare clinical entity representing less than 100 cases a year. In most cases, tumors arising in the paranasal sinuses are of the non-Hodgkin's variety. Most of these tumors are asymptomatic in the early stages and are diagnosed only after invasion of adjacent structures with local bone destruction. Computed tomography is essential for staging. The prognosis and treatment of lymphoma of the paranasal sinuses are based on the anatomic staging and histologic subtype. The prognosis is favorable for patients with localized disease. The authors describe a malignant lymphoma of the maxillary sinus in a 44-year-old man.