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Discovery and Biological Evaluation of

التفاصيل البيبلوغرافية
العنوان:	Discovery and Biological Evaluation of
المؤلفون:	Eunsun, Park, Sun Joo, Lee, Heegyum, Moon, Jongmi, Park, Hyeonho, Jeon, Ji Sun, Hwang, Hayoung, Hwang, Ki Bum, Hong, Seung-Hee, Han, Sun, Choi, Soosung, Kang
المصدر:	Journal of medicinal chemistry. 64(2)
سنة النشر:	2021
مصطلحات موضوعية:	Liver Cirrhosis, Models, Molecular, Wound Healing, Janus Kinase 1, Cell Line, Substrate Specificity, Mice, Structure-Activity Relationship, Gene Expression Regulation, Transforming Growth Factor beta, Drug Design, Drug Discovery, Hepatic Stellate Cells, Animals, Humans, Protein Kinase Inhibitors
الوصف:	Janus kinase 1 (JAK1) plays a key role in most cytokine-mediated inflammatory and autoimmune responses through JAK/STAT signaling; thus, JAK1 inhibition is a promising therapeutic strategy for several diseases. Analysis of the binding modes of current JAK inhibitors to JAK isoforms allowed the design of
تدمد:	1520-4804
URL الوصول:	https://explore.openaire.eu/search/publication?articleId=pmid________::6ebfb5496d50c96d277ce06804bc8110 https://pubmed.ncbi.nlm.nih.gov/33428419
رقم الأكسشن:	edsair.pmid..........6ebfb5496d50c96d277ce06804bc8110
قاعدة البيانات:	OpenAIRE

الوصف
تدمد:	15204804