This study was undertaken to compare postoperative sensitivity in posterior class I restorations using etch-and-rinse and self-etch composite resins, GC Fuji IX, and Cention-N.The sample size consisted of 160 participants. After clinical and radiographic examination, the participants were randomly assigned to four groups consisting of 40 participants each according to the restorative materials used. Class I cavity was prepared and was restored on each patient and after restoration postoperative sensitivity was evaluated at 24 h, 48 h, and 7 days using the visual analog scale (VAS). The results were tabulated and statistically analyzed using analysis of variance (ANOVA) and post-hoc multiple comparison tests.There were significant differences present between the groups at 24 h, 48 h, and 7 days. We found that the materials causing least postoperative sensitivity are ranked according to superiority as GC Fuji IXnano-hybrid composite using self-etch adhesiveCention-Nnano-hybrid composite using etch-and-rinse adhesive.Both GC Fuji IX and self-etch adhesive showed less postoperative sensitivity as compared to etch-and-rinse and Cention-N at 24 h. With GC Fuji IX and self-etch adhesive postoperative sensitivity was decreased while Cention-N also showed good results at 48 h and 7 days. Etch-and-rinse adhesive showed maximum postoperative sensitivity as compared to other groups at 24 h, 48 h, and 7 days.Teeth restored with resin composites are susceptible to sensitivity. The restorative material used and their handling can influence postoperative sensitivity.
