To examine the potential role of Medical Information Database Network (MID-NETThe pilot studies were designed to address three major objectives in postmarketing drug safety assessments, ie, the examination of actual drug utilization, the impact of safety-related regulatory actions, and drug-associated risks. The five studies were conducted on the following topics: (a) utilization of codeine-containing products and its relationship with respiratory depression, (b) impact of a Dear Healthcare Professional letter on hypocalcemia incidence associated with denosumab (RanmarkThe pilot studies were successfully conducted and demonstrated the value of MID-NETMID-NET
