Comparison of outcomes for percutaneous coronary intervention in men and women with unprotected left main disease

التفاصيل البيبلوغرافية
العنوان: Comparison of outcomes for percutaneous coronary intervention in men and women with unprotected left main disease
المؤلفون: Sheng-Wen, Liu, Chang-Dong, Guan, Feng-Huan, Hu, Jue, Chen, Ke-Fei, Dou, Wei-Xian, Yang, Yong-Jian, Wu, Yue-Jin, Yang, Bo, Xu, Shu-Bin, Qiao
المصدر: Journal of Geriatric Cardiology : JGC
سنة النشر: 2021
مصطلحات موضوعية: cardiovascular diseases, Research Article
الوصف: BACKGROUND Percutaneous coronary intervention (PCI) in patients with unprotected left main coronary artery disease (ULMCAD) is increasing strategy in coronary artery patients. However, there is a lack of knowledge on the impact of sex on outcomes of patients undergoing ULMCAD PCI. METHODS From January 2004 to December 2015, there were 3,960 patients undergoing ULMCAD PCI at our institution, including 3,121 (78.8%) men and 839 (21.2%) women. The clinical outcome included the incidence of major adverse cardiac events (MACE) (the composite of all-cause death, myocardial infarction (MI), and revascularization), all-cause death, MI, revascularization at three years follow-up. RESULTS Compared with men, women had not significantly different MACE (14.7% vs. 14.6%, P = 0.89, all-cause death (3.5% vs. 3.7%, P = 0.76), MI (5.0% vs. 4.3%, P = 0.38), revascularization (9.1% vs. 8.9%, P = 0.86), respectively. After adjustment, rates of MACE (HR = 1.49; 95% CI: 1.24−1.81;P < 0.0001) and all-cause death (HR = 1.65; 95% CI: 1.09−2.48; P = 0.017) occurred more frequently in male patients, as well as revascularization (HR = 1.46; 95% CI: 1.16−1.85;P = 0.001). CONCLUSION In this analysis, compared to men, women undergoing ULMCAD PCI have better outcomes of MACE, all-cause death, and revascularization.
تدمد: 1671-5411
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::900e1fa47442649673e054455d96065b
https://pubmed.ncbi.nlm.nih.gov/33907546
حقوق: OPEN
رقم الأكسشن: edsair.pmid..........900e1fa47442649673e054455d96065b
قاعدة البيانات: OpenAIRE