Positional Sleep Apnea Among Regional and Remote Australian Population and Simulated Positional Treatment Effects

التفاصيل البيبلوغرافية
العنوان: Positional Sleep Apnea Among Regional and Remote Australian Population and Simulated Positional Treatment Effects
المؤلفون: Himanshu, Garg, Xin Yi, Er, Timothy, Howarth, Subash S, Heraganahally
المصدر: Nature and Science of Sleep
سنة النشر: 2020
مصطلحات موضوعية: adherence: apnea hypopnea index, body mass index, positional therapy, continuous positive airway pressure, obstructive sleep apnea, respiratory tract diseases, Original Research
الوصف: Purpose To assess the prevalence of positional sleep apnea (POSA) and its predictors in patients diagnosed to have obstructive sleep apnea (OSA) in the regional and remote population of the Northern Territory of Australia over a two-year study period (2018 and 2019). Patients and Methods Of the total 1463 adult patients who underwent a diagnostic polysomnography (PSG), 946 patients were eligible to be included in the study, of them, 810 consecutive patients with OSA (Apnea-Hypopnea Index (AHI) ≥ 5) who slept >4 h and had ≥30 min sleep in both supine and lateral positions were assessed. Patients were considered to have POSA if supine AHI to lateral AHI ratio ≥2. The likely comparative impact of use of continuous positive airway therapy (CPAP) or positional therapy (PT) on disease severity was evaluated using model simulation. Results A total of 495/810 (61%) patients had POSA, the majority were males (68% vs 60%, p=0.013) and non-Indigenous Australians (93% vs 87%, p=0.004). POSA patients were younger (mean difference 2.23 years (95% CI 0.27, 4.19)), less obese (BMI mean difference 3.06 (95% CI 2.11, 4.01)), demonstrated less severe OSA (p < 0.001) and a greater proportion reported alcohol consumption (72% vs 62%, p=0.001) as compared to those with non-POSA. Using the simulation model, if patients with POSA use PT two-thirds (323/495, 65%) would obtain significant improvement of their OSA severity, with one in five (92/495, 19%) displaying complete resolution. Comparing this to simulated CPAP therapy, where the majority (444/495, 90%) will show significant improvement, and one-third (162/495, 33%) will display complete resolution. Conclusion POSA needs to be routinely recognised and positional therapy integrated in practice especially in the remote regions and in the developing world when effective methods are in place to monitor positional therapy.
تدمد: 1179-1608
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::abe2fbb4fadbd05960e9c990230039a4
https://pubmed.ncbi.nlm.nih.gov/33304112
حقوق: OPEN
رقم الأكسشن: edsair.pmid..........abe2fbb4fadbd05960e9c990230039a4
قاعدة البيانات: OpenAIRE