Epidemiology of symptomatic infective anoproctitis in a population of men having sex with men (MSM)

التفاصيل البيبلوغرافية
العنوان: Epidemiology of symptomatic infective anoproctitis in a population of men having sex with men (MSM)
المؤلفون: J, Lourtet-Hascoet, L, Mine, L, Spindler, B, Pilmis, M, Aubert, A, El Mituialy, V, Vieillefond, V, de Parades, A, Le Monnier
المصدر: Infection. 50(4)
سنة النشر: 2021
مصطلحات موضوعية: Male, Gonorrhea, Sexual and Gender Minorities, Coinfection, Prevalence, Humans, Chlamydia trachomatis, Chlamydia Infections, Homosexuality, Male, Neisseria gonorrhoeae, Anti-Bacterial Agents
الوصف: Anoproctitis due to Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) are Sexual Transmitted Infections (STIs) reported in MSM population. This study describes clinical and microbiological epidemiology of infective anoproctitis in MSM population.All patients with symptomatic anoproctitis consulting at the proctology Institute of Saint-Joseph's Hospital, Paris, were included. Detection of CT/NG was performed by PCR GeneXpertSymptoms most frequently reported were pain, rectal bleeding and purulent flow in 66%, 52% and 49% of cases, respectively. On the 311 rectal samples collected, 171 (55.2%) were positive to CT/NG. Among the 194 used for mPCR, 148 were positive to STIs pathogens (76.2%) including 106 samples (71.6%) positive in coinfections. Among NG infections, 22.6% of the strains were resistant to azithromycin and 26.8% to tetracyclines.Anorectal infections in this MSM population showed a high prevalence of not only CT/NG but also other pathogens involved in STIs. The high level of coinfections confirms the requirement of accurate PCR tests to improve diagnosis. This study describing increasing antibiotic resistances for NG strains confirms the updating of international guidelines on antibiotic treatments recommendations.
تدمد: 1439-0973
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::ca572d65995f00350cd43b1e5613e14f
https://pubmed.ncbi.nlm.nih.gov/35212944
رقم الأكسشن: edsair.pmid..........ca572d65995f00350cd43b1e5613e14f
قاعدة البيانات: OpenAIRE