Effect of low-level 1800 MHz radiofrequency radiation on the rat sciatic nerve and the protective role of paricalcitol

التفاصيل البيبلوغرافية
العنوان: Effect of low-level 1800 MHz radiofrequency radiation on the rat sciatic nerve and the protective role of paricalcitol
المؤلفون: Ulku, Comelekoglu, Savas, Aktas, Burcu, Demirbag, Meryem Ilkay, Karagul, Serap, Yalin, Metin, Yildirim, Aysegul, Akar, Begum, Korunur Engiz, Fatma, Sogut, Erkan, Ozbay
المصدر: Bioelectromagnetics. 39(8)
سنة النشر: 2018
مصطلحات موضوعية: Male, Radio Waves, Ergocalciferols, Animals, Radiation-Protective Agents, Rats, Wistar, Sciatic Nerve, Electrophysiological Phenomena, Rats
الوصف: The nervous system is an important target of radiofrequency (RF) radiation exposure since it is the excitable component that is potentially able to interact with electromagnetic fields. The present study was designed to investigate the effects of 1,800 MHz RF radiation and the protective role of paricalcitol on the rat sciatic nerve. Rats were divided into four groups as control, paricalcitol, RF, and RF + paricalcitol. In RF groups, the rats were exposed to 1,800 MHz RF for 1 h per day for 4 weeks. Control and paricalcitol rats were kept under the same conditions without RF application. In paricalcitol groups, the rats were given 0.2 μg/kg/day paricalcitol, three times per week for 4 weeks. Amplitude and latency of nerve compound action potentials, catalase activities, malondialdehyde (MDA) levels, and ultrastructural changes of sciatic nerve were evaluated. In the RF group, a significant reduction in amplitude, prolongation in latency, an increase in the MDA level, and an increase in catalase activity and degeneration in the myelinated nerve fibers were observed. The electrophysiological and histological findings were consistent with neuropathy, and the neuropathic changes were partially ameliorated with paricalcitol administration. Bioelectromagnetics. 39:631-643, 2018. © 2018 Wiley Periodicals, Inc.
تدمد: 1521-186X
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::caef529adba3565ea75b72e10dbfd296
https://pubmed.ncbi.nlm.nih.gov/30328127
رقم الأكسشن: edsair.pmid..........caef529adba3565ea75b72e10dbfd296
قاعدة البيانات: OpenAIRE