Echocardiographic estimate of pulmonary artery pressure in sarcoidosis patients - real world data from a multi-national study
| العنوان: | Echocardiographic estimate of pulmonary artery pressure in sarcoidosis patients - real world data from a multi-national study |
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| المؤلفون: | Huitema, Marloes P, Post, Marco C, Grutters, Jan C, Wells, Athol U, Kouranos, Vasilis, Shlobin, Oksana A, Nathan, Steven D, Culver, Daniel A, Barney, Joseph, Gupta, Rohit, Carmona, Eva, Alhamad, Esam H, Scholand, Mary B, Wijsenbeek, Marlies, Ganesh, Sivagini, Lower, Elyse E, Engel, Peter J, Baughman, Robert P |
| المساهمون: | Cardiology, Pulmonary Medicine |
| المصدر: | Sarcoidosis, Vasculitis, and Diffuse Lung Diseases Sarcoidosis Vasculitis and Diffuse Lung Diseases, 38(4):e2021032. Mattioli 1885 S.p.A. |
| بيانات النشر: | Mattioli 1885, 2022. |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Original Article: Clinical Research, pulmonary hypertension, echocardiography, sarcoidosis |
| الوصف: | INTRODUCTION: Echocardiographic measurement of the right ventricular systolic pressure (RVSP) is commonly used for estimating systolic pulmonary artery pressure (PASP) measured during right heart catheterization (RHC) in patients suspected for pulmonary hypertension (PH). Generally, there seems to be a strong correlation. However, this has been reported as less robust in sarcoidosis. We aim to investigate the correlation between RVSP and RHC measurements using real world data and analyzed factors influencing the relationship between RVSP and PASP in sarcoidosis. METHODS & RESULTS: Data of patients with and without sarcoidosis associated PH who had both a measurable echocardiographic RVSP and invasive PASP were collected from the RESAPH registry, PULSAR study and Cincinnati Sarcoidosis Clinic database (n=173, 60.1% female, mean age 56.0±9.5 years). Among them, 124 had PH confirmed by RHC. There was a strong correlation between RVSP and PASP (r=0.640). This correlation was significant in both male and female, white or non-white, forced vital capacity (FVC) >60%, and presence of fibrosis (p 10mmHg. Inaccurate echocardiographic estimation of the invasive PASP occurred in 50.8%, with overestimation mostly in patients without PH, and underestimation in patients with severe PH. An RVSP>50mmHg was associated with worse survival. CONCLUSIONS: In this real world multicenter cohort of sarcoidosis patients, we found a significant correlation between RVSP as determined by echocardiography and invasive PASP. Over- or underestimation of PASP occurred frequently. Therefore, echocardiographic RVSP measurement alone to screen for PH in sarcoidosis should be used with caution. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2532-179X 1124-0490 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::024bdd0e6d6879db0ef14774718f1114 http://europepmc.org/articles/PMC8787381 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.pmid.dedup....024bdd0e6d6879db0ef14774718f1114 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 2532179X 11240490 |
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