Androgen therapy and atherosclerotic cardiovascular disease
| العنوان: | Androgen therapy and atherosclerotic cardiovascular disease |
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| المؤلفون: | McGrath, K-CY, McRobb, LS, Heather, AK |
| المصدر: | Vascular Health and Risk Management |
| بيانات النشر: | Dove Medical Press, 2008. |
| سنة النشر: | 2008 |
| مصطلحات موضوعية: | Clinical Trials as Topic, Cardiovascular System & Hematology, Arteriosclerosis, Cardiovascular Diseases, Risk Factors, Androgens, Animals, Humans, Review |
| الوصف: | Cardiovascular disease (CVD) remains the leading cause of death in Western society today. There is a striking gender difference in CVD with men predisposed to earlier onset and more severe disease. Following the recent reevaluation and ongoing debate regarding the estrogen protection hypothesis, and given that androgen use and abuse is increasing in our society, the alternate view that androgens may promote CVD in men is assuming increasing importance. Whether androgens adversely affect CVD in either men or women remains a contentious issue within both the cardiovascular and endocrinological fraternities. This review draws from basic science, animal and clinical studies to outline our current understanding regarding androgen effects on atherosclerosis, the major CVD, and asks where future directions of atherosclerosis-related androgen research may lie. |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 1178-2048 1176-6344 |
| URL الوصول: | https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::51aa49ce8b5b4db01337f9b69365fb68 http://europepmc.org/articles/PMC2464747 |
| حقوق: | OPEN |
| رقم الأكسشن: | edsair.pmid.dedup....51aa49ce8b5b4db01337f9b69365fb68 |
| قاعدة البيانات: | OpenAIRE |
PDF full text from Publisher | تدمد: | 11782048 11766344 |
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